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临床试验/RBR-65qchvs
RBR-65qchvs进行中(未招募)Unknown

Efficacy evaluation of using Autologous tooth-derived Graft material in post-extraction dental socket preservation

niversidade Tishreen0 个研究点开始时间: 2024年5月28日最近更新:

试验速览

阶段
Unknown
状态
进行中(未招募)
发起方

研究概览

简要总结

Introduction Preserving the structural integrity of the alveolar ridge is paramount in ensuring the success of dental implant procedures and optimizing both aesthetic and physiological outcomes. This study aims to evaluate the efficacy of autologous dental grafting and explore intriguing results achieved through the utilization of allogeneic dental grafts obtained from a familial participant within the study's framework. Objectives Preserving the structural integrity of the alveolar ridge is paramount in ensuring the success of dental implant procedures and optimizing both aesthetic and physiological outcomes. This study aims to evaluate the efficacy of autologous dental grafting and explore intriguing results achieved through the utilization of allogeneic dental grafts obtained from a familial participant within the study's framework. Methods Eleven patients necessitating bilateral dental extractions were enrolled in the study. Ten patients underwent autologous dental grafting on one side, while the contralateral side remained untreated. In the eleventh case, one side received autogenous dental grafting, while the other side was augmented with an allogeneic graft sourced from the patient's son. Outcomes were monitored over a four-month period. Results Autogenous dental grafting led to a significant enhancement in bone density values and a reduction in osseous absorption rates(P<0.05) when compared to untreated sites among the ten patients who underwent the procedure. However, notable advancements were observed in patient 11 who received an allogeneic dental graft from a familial donor, suggesting potential superiority over autologous grafting in promoting bone regeneration. These findings underscore the promising prospects of employing allogeneic dental grafts sourced from family members to achieve optimal outcomes in alveolar ridge preservation. Conclusions The study underscores the significance of utilizing autologous dental grafts for preserving alveolar ridge dimensions. Importantly, the noteworthy improvement observed in patient outcomes resulting from the use of allogeneic dental grafts compared to autologous grafts raises several inquiries, particularly concerning the potential relationship between the patient and the donor.

研究设计

研究类型
Interventional

入排标准

年龄范围
18Y 至 64Y(—)

入选标准

  • Patients of both genders; Individuals aged 18 to 64 years; non smokers; non-alcoholics; medically fit patients (no previous medical conditions such as heart, diabetes, hypertension, etc.); with indication of extraction of symmetrical teeth; integrity of dental sockets after extraction; patients who signed Informed Consent and attended follow-up sessions

排除标准

  • Smokers; alcoholic; patients with infections in the gums or alveoli

研究者

发起方
niversidade Tishreen

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