JPRN-UMIN000000564已完成2 期
Phase II trial of docetaxel and carboplatin in patients with stage IVb or recurrent nonsquamous cell carcinoma of uterine cervix - Phase II trial of docetaxel and carboplatin in patients with stage IVb or recurrent nonsquamous cell carcinoma of uterine cervix
Sankai Gynecology Study Group0 个研究点目标入组 50 人开始时间: 2007年1月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 50
研究概览
简要总结
The response rate was 47.9% with 5 patients achieving complete response, 18 partial response, 14 stable disease, and 6 progressive disease. The disease control rate was 77.1%. With a median follow-up duration of 368 days, the median progression-free survival and overall survival were 6.1 months (95% CI 5.5-8.6) and 15.8 months (95% CI 18.2-28.3), respectively.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 75years-old（—）
- 性别
- Female
入选标准
- 未提供
排除标准
- •1.Fever with over 38.0C 2.Infection or WBC>12,000/mm3 3.Severe complications 4.Neuropathy >Grade 2 5.Edema > Grade 2 6.Double cancer 7.Massive pleural effusion and ascites 8.Hypersensitivity reactions to docetaxel or carboplatin 9.Patients judged as exclusive case by the investigator
研究者
相似试验
已完成
2 期
Phase II trial of dosetaxel and carboplatin as neoadjuvant chemotherapy in patients with stage Ib2-II nonsquamous cell carcinoma of uterine cervixnonsquamous cell carcinoma of uterine cervixJPRN-UMIN000000560Sankai Gynecology Study Group (SGSG)61
Unknown
2 期
Cisplatin,Docetaxel and S-1 for Advanced Gastric and Gastroesophageal Junction CancerGastroesophageal Junction CancerGastric CancerNCT01747707Chinese Academy of Medical Sciences40
已完成
2 期
A Study of Carboplatin and DOXIL Plus Bevacizumab in Patients With Platinum Sensitive Recurrent Ovarian, Fallopian Tube and Primary Peritoneal CancersOvarian NeoplasmsFallopian Tube NeoplasmsPeritoneal NeoplasmsNCT00698451Johnson & Johnson Pharmaceutical Research & Development, L.L.C.54
已完成
1 期
Phase I/II trial of Nedaplatin and Docetaxel for advanced Squamous cell carcinoma of the lungchamotherapy-naive advanced squamous cell carcinoma of the lungJPRN-UMIN000001227ational Cancer Center Hospital East Thoracic Oncology Division24
进行中（未招募）
1 期
A Phase II Trial of docetaxel, cisplatin and 5FU chemotherapy in locally advanced and metastatic carcinoma of the penis - Penile TPFocally advanced and metastatic carcinoma of the penisMedDRA version: 13.1Level: LLTClassification code 10034299Term: Penile cancerSystem Organ Class: 10029104 - Neoplasms benign, malignant and unspecified (incl cysts and polyps)EUCTR2008-000707-28-GBThe Institute of Cancer Research29