Do Adhesive Flash-free Brackets Affect Bacterial Plaque? A Randomized Controlled Clinical and Microbiological Assessment
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 主要终点
- development of white spot lesion (WSL)
研究概览
简要总结
This study aimed to compare flash-free bracket system with conventional adhesive-coated bracket system in patients with maxillary crowding.
详细描述
Aim: The aim of this split-mouth study was to compare conventional and adhesive flash-free-bracket systems in terms of plaque retention, white spot lesion formation, biomarker levels and select microbes in gingival crevicular fluid (GCF).
Materials & Methods: Thirty-seven systemically healthy patients (18 males, 19 females) with the age range of 13-18 years were involved in this split-mouth study. Clinical evaluations, quantitative light-induced fluorescence (QLF) imaging, GCF and plaque samplings were performed at baseline and at 1-, 2-, 3-months. QLF was repeated following debonding, GCF samples were analyzed by immunoassay and real-time PCR for the biomarker and bacteria content. Data were analyzed by Wilcoxon on dependent samples.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Factorial
- 主要目的
- Treatment
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 13 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •being systemically healthy
- •having 4-7 mm maxillary crowding with a maximum of 2 mm linear displacement of contact points and non-extraction treatment planning.
排除标准
- 未提供
研究组 & 干预措施
Flash-free bracket group
Orthodontic treatment with flash-free bracket system
干预措施: orthodontic treatment (Procedure)
Control
Orthodontic treatment with conventional adhesive-coated brackets
干预措施: orthodontic treatment (Procedure)
结局指标
主要结局
development of white spot lesion (WSL)
时间窗: 1 month
WSL is the first sign of caries
次要结局
- plaque accumulation around the brackets(1 month)
- microbial composition around the brackets(1 month)