Effects of Combined Heat Application and Acupressure to the Carotid Artery Region on Cerebral Blood Flow in Healthy Adults: An Investigator-Initiated, Single-Group, Single-Center, Prospective Case Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 9
- 试验地点
- 1
- 主要终点
- A SPECT CT brain scan
研究概览
简要总结
The aim of this study is to investigate the effects of combined heat application and acupressure to the carotid artery region on cerebral blood flow in healthy adults
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 40 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Adults aged 40 to 65 years.
- •Individuals with no history of cerebrovascular, cardiovascular, or neurological diseases.
- •Individuals who have signed the informed consent form and voluntarily agreed to participate in the study
排除标准
- •Individuals with a history of cerebrovascular, cardiovascular, or neurological diseases (e.g., stroke, angina, epilepsy).
- •Individuals currently taking medications that may affect cerebral blood flow (such as antihypertensive agents or antidepressants).
- •Individuals with skin diseases or lesions that make it difficult to apply heat or acupressure devices to the carotid artery region, and individuals who are pregnant or breastfeeding.
- •Individuals with a history of seizures.
- •Individuals who have participated in clinical studies two or more times in the same year, or who have participated in another clinical study within the past 6 months.
- •Individuals who, in the judgment of the principal investigator or sub-investigator, have clinically significant findings that make them unsuitable for participation in this study.
结局指标
主要结局
A SPECT CT brain scan
时间窗: In the post-SPECT protocol, the radiopharmaceutical will be administered at 5 minutes (n=3), 10 minutes (n=3), and 20 minutes (n=3) after the start of image acquisition.
Cerebral blood flow change rate analysis: For each participant, the percentage change in cerebral blood flow (CBF) observed on SPECT imaging compared with the baseline time point will be quantitatively analyzed at the following three time points. Radiopharmaceutical injection reference times: 5 minutes, 10 minutes, and 20 minutes after injection.
次要结局
未报告次要终点
研究者
Yong-il Shin
Professor
Pusan National University Yangsan Hospital