Assessment of Complete Response MRI Criterion After Neoadjuvant Therapy in Locally Advanced Rectal Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 99
- 试验地点
- 1
- 主要终点
- Complete response MRI criterion
研究概览
简要总结
Standard care for locally advanced rectal cancer consists in a neoadjuvant therapy followed by surgery. Morbidity and mortality remain high after rectal surgery, and often linked with quality of life impairment. 10 to 30% present a pathological complete response after neoadjuvant therapy. Some surgical teams propose "watch and wait" approach for patients selected with clinical complete responses criterion. The problem is to be sur the response is complete. MRI seems to be accurate to select complete responders. We will try to find MRI criterion of complete responses.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Rectal adenocarcinoma
- •Locally advanced
- •Neoadjuvant therapy
- •MRI restaging
- •Rectal surgery
- •Definitive anatomopathology study
排除标准
- 未提供
结局指标
主要结局
Complete response MRI criterion
时间窗: Day 0: immediately after the procedure
We selected several objective MRI criterion among literature and compared them between the two groups.
次要结局
- MRI accuracy(Day 0: immediately after the procedure)
