Evaluation Of Deep Anterior Lamellar Keratoplasty By Anterior Segment Ocular Coherence Tomography
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 主要终点
- To evaluate the post-operative changes after DALK surgery through ant segment OCT and its relation to clinical findings.
研究概览
简要总结
Investigators' research is concerned observing the post-operative anterior segment OCT changes throughout the post- operative follow up of the patient and relating to improve the visual outcome of the surgery which is the goal of surgery
详细描述
Study tools (in detail, e.g., lab methods, instruments, steps, chemicals, ...):
- Complete medical and ocular history, including patients' age, sex, type of pathology of the cornea such as keratoconus, opacity , history of previous corneal intervention , and other ocular surgeries.
- Thorough ophthalmological examination, including visual acuity, intraocular pressure (IOP) measuring by Goldman applanation tonometer (Haag Streit, Koeniz, Switzerland), slit lamp biomicroscopic examination of anterior segment, investigations for keratoconus as pentacam , preoperative anterior segment OCT if needed , slit lamp photography for the cornea .
Candidate patients will be operated through DALK , then will be examined post operative clinically and be followed up at 3 months , 6 months for best corrected visual acuity, Intraocular pressure , refraction , graft healing , and anterior segment OCT for the anterior chamber angel , graft healing , descemet's membrane state , tear film . The interpretation of the clinical data with the changes in the ant. Segment OCT will give us the clue to get the best visual outcome of surgery .
2.4.5 -Research outcome measures:
- Primary (main):
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing DALK surgery older than 18 years old ( keratoconus and corneal opacity ).
排除标准
- •Patients suffering from active corneal ulcer
- •Active infection.
- •Posterior segment diseases.
- •Recent ocular surgery in the study eye in the 2 months prior to enrolment,
- •Media opacities as vitreous haemorrhage,
- •Vasculitis , patients with macular edema related to, glaucoma, chronic uveitis, or pre-existing ocular pathologic features or abnormalities.
结局指标
主要结局
To evaluate the post-operative changes after DALK surgery through ant segment OCT and its relation to clinical findings.
时间窗: 6 months after the surgery
To evaluate the post-operative changes after DALK surgery through ant segment OCT and its relation to clinical findings.
次要结局
- To Improve sugery(6 months after the surgery)
研究者
Ali Omar Mohamed Ali
Principal Investigator
Assiut University