Determinants of Rescue Ventilation Requirement in Airway Surgery Under General Anesthesia With Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE): A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Time to Rescue Ventilation Due to Hypoxemia During Airway Surgery With THRIVE Under General Anesthesia
研究概览
简要总结
The anesthesia and surgical procedures from the time the patient enters the operating room to discharge from the recovery room are identical to those used in conventional airway surgeries performed under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE). The time point at which rescue ventilation is required due to a drop in oxygen saturation below 92% during anesthesia will be recorded, and the predictive factors for this event will be investigated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients undergoing elective airway surgery under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE)
- •Patients who provide written informed consent
排除标准
- •Patients who decline to participate in the study
研究组 & 干预措施
THRIVE
Adult patients undergoing airway surgery under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE).
结局指标
主要结局
Time to Rescue Ventilation Due to Hypoxemia During Airway Surgery With THRIVE Under General Anesthesia
时间窗: From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period)
The primary outcome is the time from the start of apnea to the initiation of rescue ventilation, defined as the point when oxygen saturation (SpO₂) falls to 92% or below during airway surgery under general anesthesia with Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE). This will be measured using continuously recorded intraoperative data. The aim is to identify clinical predictors (e.g., anatomical and physiological variables) associated with the need for rescue ventilation.
次要结局
- Lowest Oxygen Saturation After Initiation of Rescue Ventilation(From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period))
- Time to Recovery of SpO₂ to 100% After Rescue Ventilation(From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period))
- End-Tidal CO₂ at the Time of Rescue Ventilation(From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period))
- Predictive Factors for the Requirement of Rescue Ventilation(From the start of apnea to the initiation of rescue ventilation during surgery (intraoperative period))
研究者
Shin Kyung Won, MD
Clinical instructor
Seoul National University Hospital