ONG-TERM OXYGEN THERAPY (LTOT) IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) PATIENTS WITH MODERATE CHRONIC HYPOXEMIA AND CHRONIC HEART FAILURE - LTOT IN COPD WITH CHRONIC HYPOXEMIA AND CHF

AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI0 个研究点开始时间: 2008年6月5日最近更新: 2012年3月19日

适应症

试验速览

暂无简介。

•A patient will be eligible for inclusion in this study if all of the following criteria are met: 1. Male or female outpatients, aged 40-80 years inclusive, with a baseline post-bronchodilator FEV1 <80% of predicted normal, and post-bronchodilator FEV1/VC<70%. 2. An established clinical history of COPD according to the GOLD (5) 3. Moderate and stable chronic hypoxemia at rest (55< PaO2<65 mmHg) detected on 5 measurements separated by at least 2 weeks 4. Clinical signs of chronic heart failure according to the European Society of Cardiology (ESC) criteria (16), as certified by the local cardiology specialist 5. Ex smokers with > 20 pk/years having stopped for at least 3 months
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Patients will be excluded from the study if they have: 1.congenital heart disease, 2.lung cancer, or other cancers, 3.restrictive disorder (e.g. tuberculosis sequelae, interstitial pulmonary diseases); 4. other clinically significant coexisting severe diseases that could influence the survival in the study period.

发起方

AZIENDA OSPEDALIERA UNIVERSITARIA CAREGGI