Prognostic Factors Impacting Surgical Resection Outcomes in Patients With Brain
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Functional outcome of patients undergoing surgery for brain metastasis
研究概览
简要总结
While many studies have investigated the prognostic factors for patients undergoing surgical resection for primary brain tumors, decision-making for patients with brain metastasis (BM) is more complex because of their higher burden of comorbidities compared to those with primary brain tumors. In addition, although various prognostic indicators have been identified to predict prognosis in several types of cancer, such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and systemic immune-inflammation index (SII), limited studies have yet determined which group of patients would yield beater survival outcome after surgical resection for BM. This study aimed to investigate the impact of patient and perioperative characteristics and prognostic indicators on survival outcome of patients undergoing surgical resection of BM.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients with Clinical diagnosis of brain metastasis
- •patients who underwent craniotomy surgery for brain metastasis
排除标准
- •patients with insufficient data for associated factors
- •patients who underwent stereotactic biopsy for brain metastasis
- •patients who did not undergo craniotomy surgery for brain metastasis
结局指标
主要结局
Functional outcome of patients undergoing surgery for brain metastasis
时间窗: from date of surgery until 6 months after surgery ordate of death from any cause, whichever came first
change of preoperative and postoperative modified rankin scale
survival outcome of patients undergoing surgery for brain metastasis
时间窗: From date of surgery until the date of death from any cause, whichever came first, assessed up to 100 months
overall survival of patients
次要结局
未报告次要终点
