跳至主要内容
临床试验/NCT06318065
NCT06318065招募中不适用

Prognostic Factors Impacting Surgical Resection Outcomes in Patients With Brain

National Cheng-Kung University Hospital1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2010年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
100
试验地点
1
主要终点
Functional outcome of patients undergoing surgery for brain metastasis

研究概览

简要总结

While many studies have investigated the prognostic factors for patients undergoing surgical resection for primary brain tumors, decision-making for patients with brain metastasis (BM) is more complex because of their higher burden of comorbidities compared to those with primary brain tumors. In addition, although various prognostic indicators have been identified to predict prognosis in several types of cancer, such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), prognostic nutritional index (PNI), and systemic immune-inflammation index (SII), limited studies have yet determined which group of patients would yield beater survival outcome after surgical resection for BM. This study aimed to investigate the impact of patient and perioperative characteristics and prognostic indicators on survival outcome of patients undergoing surgical resection of BM.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • patients with Clinical diagnosis of brain metastasis
  • patients who underwent craniotomy surgery for brain metastasis

排除标准

  • patients with insufficient data for associated factors
  • patients who underwent stereotactic biopsy for brain metastasis
  • patients who did not undergo craniotomy surgery for brain metastasis

结局指标

主要结局

Functional outcome of patients undergoing surgery for brain metastasis

时间窗: from date of surgery until 6 months after surgery ordate of death from any cause, whichever came first

change of preoperative and postoperative modified rankin scale

survival outcome of patients undergoing surgery for brain metastasis

时间窗: From date of surgery until the date of death from any cause, whichever came first, assessed up to 100 months

overall survival of patients

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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