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临床试验/NCT00519402
NCT00519402撤回不适用

Outcomes of Partial Versus Complete Tonsillectomy for Obstructive Sleep Disordered Breathing in Children

The Cleveland Clinic1 个研究点 分布在 1 个国家开始时间: 2007年8月22日最近更新:
适应症

试验速览

阶段
不适用
状态
撤回
试验地点
1

研究概览

简要总结

Introduction: There is currently no long-term study, which compares the outcomes of partial tonsillectomy to conventional tonsillectomy. We hypothesize that there will be little significant tonsillar regrowth with partial tonsillectomy.

Background and Significance: Tonsillectomy is the most common major surgical procedure performed on children in the United States with nearly 300,000 procedures performed each year, primarily for the indication of obstructive sleep disordered breathing (OSDB). Conventional (total) tonsillectomy removes the tonsillar capsule, and partial tonsillectomy preserves the capsule by shaving away the tonsils using an endoscopic microdebrider. Partial tonsillectomy results in less pain, fewer days to normal activity and diet, and fewer days of analgesics than total tonsillectomy. There are no significant differences between the techniques in blood loss or postoperative life improved Historical evidence suggests that eventually there will be tonsillar regrowth with partial tonsillectomy. However, in a 2003 follow-up report of 243 children undergoing partial tonsillectomy and 107 undergoing complete tonsillectomy from 1998 through 2002 for OSDB there was no evidence of significant tonsillar regrowth. (1) We will follow-up children undergoing partial or complete tonsillectomies at the Cleveland Clinic from 1998 through 2002. There will be standardized tonsillar examinations by two observers, with a third observer in cases of significant disagreement, and questionnaires evaluating sleep apnea and daytime sleepiness, and number of tonsillar infections.

If there are a large number of children with recurrent tonsillar symptoms post partial tonsillectomy, the procedure should be abandoned. However, if follow-up reveals comparable tonsillar symptoms for partial and the total tonsillectomy, perhaps the partial procedure should replace the total tonsillectomy as the standard operation to relieve tonsillar OSDB. This could eventually result in millions of less lost days of work and school in the United States.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
5 Years 至 28 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Pediatric patients undergoing tonsillectomies at the Cleveland Clinic from 1998-2002

排除标准

  • 未提供

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

michael macknin

Staff, General Pediatrics

The Cleveland Clinic

研究点 (1)

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