NCT06741137招募中不适用
A Pilot Study of the Effect of the Combination of Inhaled Nitric Oxide and Prone Position Under EIT Monitoring on Efficacy in Patients with ARDS
Northern Jiangsu People's Hospital1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Intratidal gas distribution
研究概览
简要总结
Investigating the Impact of Combined Inhaled Nitric Oxide and Prone Positioning on the Efficacy in ARDS Patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-80 years;
- •Patients with moderate to severe ARDS on mechanical ventilation
排除标准
- •Patients with severe asthma or acute exacerbation of chronic obstructive pulmonary disease (COPD), lung tumors, post-lung resection, and post-lung transplantation.
- •Patients with hemodynamic instability requiring vasopressor support: dopamine or dobutamine >15 µg/kg/min, norepinephrine >0.3 µg/kg/min.
- •Cardiogenic pulmonary edema.
- •Patients with severe facial deformities, facial trauma, or severe thoracoabdominal trauma that precludes prone positioning ventilation.
- •Mid to late pregnancy.
- •Patients with a history of malignancy or other irreversible diseases/conditions, including those in the terminal stage.
- •Patients expected to be discharged soon or requiring invasive mechanical ventilation for less than 24 hours.
- •Patients currently participating in other studies.
结局指标
主要结局
Intratidal gas distribution
时间窗: 12 hours
次要结局
未报告次要终点
研究者
研究点 (1)
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