临床试验/JPRN-UMIN000049877

JPRN-UMIN000049877招募中Unknown

Modulation of the antidepressant and antisuicidal efficacy of low-dose ketamine infusion via the mTORC1 modulator, Rapamycin: A double-blind, randomized, placebo controlled trial combined with the neuropsychological and functional connectivity MRI study. - Modulation of the antidepressant and antisuicidal efficacy of low-dose ketamine infusion via the mTORC1 modulator, Rapamycin

Ministry of Science and Technology0 个研究点目标入组 48 人开始时间: 2023年1月1日最近更新: 2023年10月17日

适应症

试验速览

阶段: Unknown
状态: 招募中
发起方: Ministry of Science and Technology
入组人数: 48

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

暂无简介。

研究设计

研究类型: Interventional

入排标准

年龄范围: 20years-old 至 70years-old（—）
性别: All

入选标准

未提供

排除标准

•(1) Major medical conditions (e.g., head injury, epilepsy, severe renal diseases and cancer). (2) Other axis I psychiatric disorders such as schizophrenia, delusional disorder, organic brain syndrome, and dementia. (3) Pregnancy. (4) Substance abuse in previous 6 months such as cocaine, marijuana, opium, ketamine, PCP (phencyclidine). (5) Current use of NMDA receptor antagonist (Amantadine, Rimantadine, Lamotrigine, Memantine, Dextromethorphan). (6) Alcohol abuse / dependence within 6 months. (7) Attempt suicide in hospital. (8) Allergy to ketamine or rapamycin.

研究者

发起方

Ministry of Science and Technology

相似试验

Antidepressant efficacy and mechanism of add-on cognitive activation to repetitive transcranial magnetic stimulation in depressioA randomized sham-controlled study

JPRN-UMIN000008421Taipei Veterans General Hospital36

A clinical trial to study the effect of a combination therapy (oral ketamine and escitalopram) and escitalopram alone in elderly patient with depression, when given early in the course of treatment.

CTRI/2023/04/051777King George Medical University

Clinical evaluation of the antidepressant effect of the use of probiotics in bipolar disorder

RBR-5dhhhddniversidade de São Paulo

Microdose Antagonist Combination for Depression (MAC-D) Trial: combination of low dose naltrexone and flumazenil for treatment of major depressive disorderMental Health - DepressionMajor Depressive Disorder

ACTRN12621000310864Trexapharm Pty Ltd10

Are antidepressants more effective than placebo, when given in combination with mood stabilisers, in preventing mood episodes in people with bipolar I disorder?

ISRCTN90111395niversity of British Columbia (Canada)216