Predictors for Recurrence of Atrial Fibrillation After Electrical Cardioversion
试验速览
- 阶段
- 不适用
- 入组人数
- 270
- 试验地点
- 1
- 主要终点
- Atrial fibrillation recurrence
研究概览
简要总结
In patients with persistent atrial fibrillation (AF), electrical cardioversion is very effective in restoring sinus rhythm if modern, biphasic cardioverters are used. However, approximately 50 per cent of the successfully cardioverted patients experience a recurrence of AF within a few weeks. Therefore, valid predictors for AF recurrence would be of great clinical relevance, to avoid unnecessary procedures.
In the PRE-ELECTRIC study, we will investigate the predictive value of potential new biomarkers with respect to AF recurrence within 30 days after electrical cardioversion. We will investigate serum and plasma biomarkers, electrocardiological markers and echocardiographic variables in this respect. The study will be undertaken as a prospective cohort study at Bærum Hospital, Vestre Viken Hospital Trust, with national and international collaborators.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients > 18 years referred for electrical cardioversion for persistent atrial fibrillation
- •Signed, informed consent
排除标准
- •Patients < 18 years
- •Patients with paroxysmal atrial fibrillation
- •Patients unwilling to participate or without consent competence
结局指标
主要结局
Atrial fibrillation recurrence
时间窗: 30 days after electrical cardioversion
ECG-documented atrial fibrillation recurrence after successful cardioversion
次要结局
未报告次要终点