临床试验/NCT01271413

NCT01271413已完成2 期

Effects of Cognitive Training in Methadone Maintenance Patients

Johns Hopkins University2 个研究点分布在 1 个国家目标入组 134 人开始时间: 2010年12月最近更新: 2014年4月16日

适应症

试验速览

阶段: 2 期
状态: 已完成
发起方: Johns Hopkins University
入组人数: 134
试验地点: 2
主要终点: Working Memory

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This research is being done to learn if computer tasks that challenge the brain (cognitively stimulating tasks) can improve memory and other types of thinking. The study will compare the effects of different versions of the computer tasks. It also will compare the task performance of different groups of people.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Double (Participant, Outcomes Assessor)

入排标准

年龄范围: 18 Years 至 55 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

•age 18-55
•in methadone maintenance or healthy volunteers

排除标准

•Axis I disorder (except substance abuse and dependence in methadone maintenance patients)
•severe cognitive impairment
•serious untreated medical condition

结局指标

主要结局

Working Memory

时间窗: baseline, 7 weeks

Change in maximum number of digits correctly recalled in Digit Span Backwards task, from baseline to 7 weeks

次要结局

Episodic Memory(baseline, 7 weeks)
Trail-making(baseline, 7 weeks)
go/No-go(baseline, 7 weeks)
Addiction Severity Index(baseline, 7 weeks)
Delay Discounting(baseline, 7 weeks)
Digit Symbol Substitution Test(baseline, 7 weeks)

研究者

发起方

Johns Hopkins University

申办方类型

Other

责任方

Principal Investigator

主要研究者

Miriam Mintzer

Associate Professor

Johns Hopkins University

研究点 (2)

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