Observational Cohort Pilot Study on Cardiovascular Prevention in Citizens Living in Milano-Bicocca District
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Exposome
研究概览
简要总结
The main objective of the study is to characterize the cardiovascular risk profile of the population in the Bicocca district through the evaluation of the exposome and the assessment of traditional and less studied cardiovascular risk factors for cardiovascular disease.
详细描述
STUDY DURATION AND ENROLMENT
The study duration is 3 years. The study will be conducted at University of Milano-Bicocca in an ad-hoc site dedicated to the project.
STUDY POPULATION
Inclusion Criteria: Males or females age > 25 years living in the area close to University Milano-Bicocca (postcode 20126) Exclusion Criteria: Inability to sign the informed consent
STUDY PROCEDURES During the screening visit the Investigators will double check that the subject can be included according to the aforementioned inclusion and exclusion criteria.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 25 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Individuals living in the area close to University Milano-Bicocca (postcode 20126)
排除标准
- •Inability to sign the informed consent
结局指标
主要结局
Exposome
时间窗: prior index date and at baseline visit
to define the prevalence of the exposome associated with increased CV risk in an urban population. The exposome includes the following domains: 1. Internal: internal biological processes such as oxidative stress, inflammation, epigenetic changes, metabolism and the internal microbiome. 2. General external: social, economic factors, the urban environment and climate factors. 3. Specific external: an individual's immediate local environment, including exposure to chemicals, diet, physical activity, tobacco and infections.
次要结局
- Traditional CV risk factors(prior index date and at baseline visit)
- Non traditional risk factors(prior index date and at baseline visit)