Changes of Regional Tissue Oxygenation Saturation After Successful Femoral Nerve Block With Ropivacaine at Different Concentrations
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Regional tissue oxygenation saturation after successful femoral nerve block
研究概览
简要总结
Regional tissue oxygenation saturation has been shown to increase in innervated regions after sympathetic block. The aim of this prospective observational study was to evaluate the changes of regional tissue oxygenation saturation by near-infrared spectroscopy after successful femoral nerve block with ropivacaine and determine whether the changes of regional tissue oxygenation saturation can be affected by the concentration of ropivacaine.
详细描述
Successful peripheral nerve blocks induce sympathetic blockade, which increases local blood flow by vasodilation. The relationship between successful femoral nerve block and the variation of regional tissue oxygenation saturation was unclear.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Informed consent
- •American Society of Anesthesiologists physical statusⅠ-Ⅱ
- •Undergo elective elective knee arthroscopy with peripheral nerve block
排除标准
- •Refusal to participate in the study
- •Any contraindications to peripheral nerve block such as coagulation abnormalities, •Allergy to local anaesthetics, peripheral neuropathy
结局指标
主要结局
Regional tissue oxygenation saturation after successful femoral nerve block
时间窗: at 5-minute intervals till 30 minutes after regional block
rSO2
次要结局
- Pinprick sensory scores(5 minute before regional block and at 5-minute intervals till 30 minutes after regional block)
研究者
Xi Wu
Principal Investigator, Department of Anesthesiology, Union Hospital of Tongji Medical College
Huazhong University of Science and Technology