NCT00804479终止不适用
Unblinded, Multicenter, Prospective Follow-up of Long-term Consequences of Initiating Patients With Parkinson's Disease on Either Pramipexole or Levodopa.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 222
- 试验地点
- 1
- 主要终点
- We hypothesize that patients initiating therapy with pramipexole compared with levodopa will demonstrate less self-reported disability as measured by the Modified Schwab and England.
研究概览
简要总结
To determine the long-term consequences (8 years) of initiating patients with Parkinson's disease on either pramipexole or levodopa. We hypothesize that patients initiating therapy with pramipexole compared with levodopa will demonstrate less self-reported disability as measured by the Modified Schwab and England (S/E) scale 8 years after randomization.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Available 301 subjects enrolled in the CALM-PD study.
排除标准
- •Those not enrolled in the CALM-PD study.
结局指标
主要结局
We hypothesize that patients initiating therapy with pramipexole compared with levodopa will demonstrate less self-reported disability as measured by the Modified Schwab and England.
时间窗: 8 years from date randomized in CALM study
次要结局
- Our secondary specific aim is to develop and estimate a structural model that will allow us to uncover the causal pathways through which treatments effect outcomes.(8 years from randomization of CALM-PD study)
研究者
Robert Holloway
Professor
University of Rochester
研究点 (1)
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