Infiltration Between the Popliteal Artery and Capsule of the Knee Block With Adductor Canal Block With Ropivacaine vs Ropivacaine and Dexamethasone in Total Knee Arthroplasty: A Randomized Controlled Trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Time to first rescue opioid analgesia
研究概览
简要总结
Effect of adding Dexamethasone to Infiltration between the Popliteal Artery and Capsule of the Knee Block with ACB in Patients undergoing Total Knee Arthroplasty
详细描述
Knee arthroplasty is one of the most common orthopaedic procedures, especially in elderly patients, due to the deformation of joints. Patients may complain of severe pain due to surgical trauma and prostheses. Regional anaesthesia methods may be performed to reduce the inflammatory response, opioid consumption, and opioid-related side effects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 100 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •patients scheduled for total hip arthroplasty
- •patients aged >65 and <100 years
- •patients able to provide informed consent
- •patients able to reliably report symptoms to the research team
排除标准
- •inability to provide first-party consent due to cognitive impairment or a language barrier
研究组 & 干预措施
Ropivacaine
iPACK Block + ACB with Ropivacaine
干预措施: Ropivacaine (Drug)
Ropivacaine + Dexamethasone
iPACK Block + ACB with Ropivacaine + Dexamethasone
干预措施: Ropivacaine+Dexamethasone (Drug)
结局指标
主要结局
Time to first rescue opioid analgesia
时间窗: 48 hours after surgery
Time after surgery when the patient needs opiate for the first time
次要结局
- Total Opioid Consumption(48 hours after surgery)
- Numerical Rating Scale [range 0:10](48 hours after surgery)
- Nerve damage [range 0-4](48 hours after surgery)
- Quadriceps muscle strength assessed using medical research council scale [range 0:5](48 hours after surgery)
- glucose(48 hours after surgery)