NCT01801722已完成不适用
Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Percentage of patients with elevated NT-proBNP.
研究概览
简要总结
The aim of the present study was to evaluate if the analysis of NT-proBNP might be used as an initial step for the diagnosis of chronic heart failure in patients with COPD in primary health care, and to select patients for a further examination by echocardiography.
详细描述
Patients with a confirmed diagnosis of COPD were examined regarding chronic heart failure.
- An interview regarding symptoms: breathlessness, orthopnoea, night cough, nocturia, walking distance.
- Physical examination: weight and height, heart and lung auscultation, blood pressure measurement after 5 minutes' rest in the sitting position and the presence of peripheral oedema.
- Electrocardiography.
- Natriuretic peptide- NT-proBNP (Immulite 2500, Siemens Healthcare Diagnostics AB Sweden).
- Patients with the NT-proBNP level of > 1200 pg/ml were referred for echocardiography to assess left ventricular function.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged 65 years and older with the following diagnosis codes according to International Statistical Classification of Diseases and Related Health Problems - Tenth Revision:J44 (COPD) and J41, J42 (chronic bronchitis) registered during the period 1 January 2008-16 April 2008 according to the electronic patient record.
排除标准
- •Impaired cognitive function and/or anticipated difficulties in carrying out spirometry due to immobility,
- •psychiatric disorders or terminal illness.
结局指标
主要结局
Percentage of patients with elevated NT-proBNP.
时间窗: 3 months
NT-proBNP has taken only once in each patient without follow up follow up. Three months was a period when we collected data from all participants.
次要结局
- Percentage of patients with abnormal left ventricular function assessed by echocardiography. Association between elevated NT-proBNP and symptoms, signs and electrocardiography.(3 months)
研究者
Elzbieta Kaszuba
PhD student
Lund University
研究点 (1)
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