TCTR20230502003尚未招募3 期
Fluid bolus in suspected sepsis patients with hyperlactatemia: Open-labeled, Randomized controlled trial
适应症
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 224
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 N/A (No limit)（—）
- 性别
- All
入选标准
- •1) Patients who suspected sepsis: SIRS criteria > or = 2 points + suspected or confirmed source of infection.
- •2) Hyperlactatemia: Point-of-care serum lactate 2-4 mmol/L from arterial or venous blood gas.
- •3) Ages over or equal 18 years old.
排除标准
- •1) Congestive heart failure or sign of volume overload or patient who had past history of low ejection fraction (%EF less than 40%) or Functional class IV
- •2) ESRD with and without RRT
- •3) Hypotension due to any cause (SBP < 90 mmHg or MAP < 65 mmHg)
- •4) Morbid obesity (BMI > or = 40 kg/m2)
- •5) Pregnancy
- •6) Transferred from another hospital
- •7) Administration of IV fluid before ED arrival
- •8) Refused to participate or DNR
- •9) Suspected type B lactic acidosis e.g., toxin-induced (metformin, isoniazid, NRTIs), liver failure or thiamine deficiency
研究者
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