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临床试验/NCT00338975
NCT00338975已完成不适用

Cognitive Behavioral Skills Training for Schizophrenia

Veterans Medical Research Foundation2 个研究点 分布在 1 个国家目标入组 179 人开始时间: 2005年6月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
179
试验地点
2
主要终点
Social Functioning

研究概览

简要总结

This study evaluated the effectiveness of Cognitive Behavioral Social Skills Training versus goal-focused supportive contact in improving social functioning in people with schizophrenia.

详细描述

Schizophrenia is a chronic, severe, and disabling brain disorder. People with schizophrenia sometimes hear voices others don't hear, believe that others are broadcasting their thoughts to the world, or become convinced that others are plotting to harm them. These symptoms make it difficult for people with schizophrenia to interact normally and establish healthy social relationships with others. Cognitive Behavioral Social Skills Training (CBSST) is a group behavioral therapy intervention that focuses on improving cognitive and metacognitive impairments and social skills deficits that interfere with normal functioning in people with schizophrenia. Goal-focused supportive contact (GFSC) is a group therapy intervention that focuses on helping people with schizophrenia to verbalize their problems or worries and to seek advice from fellow group members. This study evaluated the effectiveness of CBSST versus GFSC in improving social functioning in people with schizophrenia. The study will assessed changes in cognition, psychotic symptoms, and use of psychiatric healthcare services.

Participants in this open label study were randomly assigned to one of the following treatment groups: treatment as usual (TAU) plus CBSST or TAU plus GFSC. Both interventions consist of 2-hour therapy sessions weekly for 36 weeks. Groups receiving each intervention do not exceed ten people. CBSST integrates cognitive therapy, social skills training, and neurocognitive compensatory aids. Cognitive therapy helps participants challenge unhelpful thoughts and build communication and problem-solving skills. Participants receive workbooks that describe the skills and contain homework assignments. GFSC focuses on empowering participants to share problems, worries, or concerns with others who face similar issues. Participants share advice with each other, but therapists do not teach skills. Outcomes were be assessed at Months 4.5, 9, 15, and 21 for all participants.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • DSM-IV diagnosis of schizophrenia or schizoaffective disorder at any stage of illness

排除标准

  • Level of care required at baseline interferes with outpatient group therapy participation (e.g., partial or inpatient hospitalization for psychiatric illness, substance use, or physical illness)
  • No case manager or care coordinator
  • Medically or psychiatrically unstable for outpatient therapy
  • Exposure to social skills training (SST), cognitive behavioral therapy (CBT), or dialectical behavioral therapy (DBT) within 5 years prior to study entry

研究组 & 干预措施

1

Experimental

Cognitive Behavioral Social Skills Training (CBSST)

干预措施: Cognitive Behavioral Social Skills Training (CBSST) (Behavioral)

1

Experimental

Cognitive Behavioral Social Skills Training (CBSST)

干预措施: Social Skills Training (Behavioral)

1

Experimental

Cognitive Behavioral Social Skills Training (CBSST)

干预措施: Goal Setting (Behavioral)

2

Active Comparator

Goal-Focused Supportive Contact (GFSC)

干预措施: Goal Setting (Behavioral)

2

Active Comparator

Goal-Focused Supportive Contact (GFSC)

干预措施: Goal-focused supportive contact (GFSC) (Behavioral)

结局指标

主要结局

Social Functioning

时间窗: Measured at baseline and Months 9 and 21

Independent Living Skills Survey (ILSS), PSR Toolkit, Maryland Assessment of Social Competence (MASC)

次要结局

  • Neuropsychological functioning(Measured at baseline and Months 9 and 21)
  • Psychotic symptoms(Measured at baseline and Months 4.5, 9, 15, and 21)
  • Cognitive insight(Measured at baseline and Months 4.5, 9, 15, and 21)

研究者

发起方
Veterans Medical Research Foundation
申办方类型
Other
责任方
Principal Investigator
主要研究者

Eric L. Granholm

Professor of Psychiatry, UCSD

San Diego Veterans Healthcare System

研究点 (2)

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