Effects of Neuromuscular Electrical Stimulation on Functional Exercise Capacity and Quality of Life in Patients With Interstitial Lung Disease
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Functional exercise capacity
研究概览
简要总结
Decreased exercise capacity and quality of life, increased dyspnea and fatigue perception and hypoxemia during exercise is seen in patients with interstitial lung disease. Impaired ventilatory response, increased lung compliance, ventilation-perfusion mismatching and inadequate peripheral circulation causes decreased exercise capacity. Another important factor that induce decreased exercise capacity is peripheral muscle weakness. In literature, there is no study investigated effects of neuromuscular electrical stimulation on functional exercise capacity, respiratory and peripheral muscle strength, pulmonary functions, physical activity level, dyspnea and fatigue perception in patients with interstitial lung disease.
详细描述
In literature, there was increased quantity of study investigated effects of neuromuscular electrical stimulation in chronic lung disease patients. It was used as a pulmonary rehabilitation component especially in patients with decreased exercise capacity and peripheral muscle strength, intensely increased dyspnea inhibits exercise. It was demonstrated that neuromuscular electrical stimulation improved functional exercise capacity, peripheral muscle strength and quality of life.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosed with interstitial lung disease
- •Clinically stable
- •Under standard medication
- •Having no exacerbation or infection
排除标准
- •Cognitive disorders
- •Orthopedic and neurological problems
- •Contraindications to apply the neuromuscular electrical stimulation (pace maker, sensory defects, etc...)
结局指标
主要结局
Functional exercise capacity
时间窗: 6 weeks
Six minute walk test
次要结局
- Depression(6 weeks)
- Generic quality of life(6 weeks)
- Disease specific quality of life(6 weeks)
- Pulmonary functions(6 weeks)
- Inspiratory and expiratory muscle strength (MIP,MEP)(6 weeks)
- Dyspnea(6 weeks)
- Peripheral muscle strength(6 weeks)
- Fatigue(6 weeks)
- Physical activity(6 weeks)
- Cough related quality of life(6 weeks)
- Maximal exercise capacity(6 weeks)
研究者
Meral Boşnak Güçlü
Assoc. Prof
Gazi University