A Study About the Role of Gut Microbiome in Fatty Liver -Fatty Pancreas and Heart Diseases .
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- prevelance of fatty pancreas 60% which is more common than the expection
研究概览
简要总结
Example 2: Interventional study The goal of this observational study is to learn know about the use of FibroScan in diagnosis of fatty pancreas in obese and non obese patients which done for the first time at worldwide as well as Egypt .The participtants already came to do liver FibroScan at center of excellence , Benha University , Egypt. Untill now the diagnosis of fatty pancreas by MRI which accurate and specific and diagnose fatty pancreasif it is more than 6.2% . lough the use of abdominal ultrasound also is proved . The use of digital fibroscan which is easy non invasive , unique as well as we can diagnose fibrosis too in the same sitting .So it is highly recommended to be add with examination of liver by fibroscan.
详细描述
This Interventional study done for subjects attend Center of excellence , at Benha University . aged of patients was from 30 years to 70 years old , both male and females , obese or non and DM or non . the patients came to do fibroscan to liver . Lab investigations in the form of CBC ,ESR , liver function tests , kidney function tests. Complete lipid profile , HbA1c .clincal and physical examinations done as regard BMI, past history for metabolic diseases , operations and blood transfusion. FibroScan done first to liver while the patients fastinf at least 3 hours with the know specific position recommendation (banana like ).The position for pancreas examination by fibroScan differe as the patient dorsal position/ recumbancy and his hand behind his head . take deep breah and slighlty keep it . some tilting to the left or right . the probe of fibroscan in the epigastrium under the left rib.which totally differe than liver which in the RT anterior axillary line 8 th intercostal space.picture taken , the unique , novality of this modility is the diagnosis of fibrosis too like liver.Grading of aftty pancreas was done as well as fibrosis of pancreas as follow :S1 =264 dB/m , S2 =276 dB/m and S3 =336 dB/m .
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
盲法说明
As we are care to early diagnosis of fatty pancreas by simple non invasive method
入排标准
- 年龄范围
- 20 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •- Subjects aged from 30 to 70 years old , both male and females , DM or not obese or non obese
排除标准
- •Exclusion Criteria:
- •Subjects with significant amount of alcohol consumption or history of alcohol consumption (>60 g/day).
- •History of steatogenic medications (amiodarone, valproic acid, corticosteroids, tetracyclines).
- •Patients with a previous history of pancreatic disease
结局指标
主要结局
prevelance of fatty pancreas 60% which is more common than the expection
时间窗: 6 months
the need to raise uo the importance to use FibroScan to diagnosis of fatty pancreas which is novel , unique and invasive , specific
次要结局
未报告次要终点
研究者
Prof.Reda Mohamed Elbadawy
professor Hepatology , Gastroenterology
Benha University
