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临床试验/CTRI/2024/03/064827
CTRI/2024/03/064827尚未招募2/3 期

Effect of Khadira (Acacia catechu Linn.) saara churna in the management of Medodushti w.s.r to Overweight and Obese individuals - An open labelled clinical trial

Dr Santhosh N1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2024年4月20日最近更新:

试验速览

阶段
2/3 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
Weight loss

研究概览

简要总结

Obesity is a serious and highly prevalant disease assosciated with increased morbidity and mortality. A thorough medical assessment is required to identify patients who are obese or at risk of obesity or obesity related complications. Considering Statistical data points, the number of obese individuals world is on ascent. As on 2022 information of WHO more than 1 billion individulas overall are obese, in that 650 million are grown ups, 340 million are teenagers and 39 million are youngsters. In India 135 million people were impacted by copulence.

The commonness of obesity in India differs because of Age, Orientation, Tophographical climate, Financial status, and so on. WHO gauges that by 2025, around 167 million adults and kids will turn out to be less healthy as a result of obesity. In the classes of obesity, Overweight and Class one oobesity is more prevalant amongst population. 

In ayurveda classics Medodushti is pathological event which causes sthoulya and atisthoulya, which comes underAshtanindita. Both the words Medovriddhi(Sthoulya) and Medo dushti are used as synonyms of each other. Medo dushti is also root cause for hazardous complications viz, Hridroga and Prameha. The Khadira is explained by Acharya Sushruta under Saalasaaradi ghana and their saara as useful part. The properties of Saalasaraadi ghana are "Mehapanduaamayahara Kaphamedovishoshana".

Bhavaprakasha explains the drug Khadira as "Tikta Kashaya Medhogna krumi meha jwara Vranaahareth" which means the drug efficiently reduces excessive meda.

Building Certainity on sungle drug therapy and minimal expense with high compelling treatment is need of great importance. Keeping this in View single drug therapy with compelling dose w.s.r to Khadira (Acacia cathechu Linn) Saara is considered for the ongoing review.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 50.00 Year(s)(—)
性别
Male

入选标准

  • Male individuals of BMI above 25 to below 35 Male individuals aged between 18 to 50 years fulfilling diagnostic criterias.

排除标准

  • Patients having BMI below 25 and above 35 Female Individuals Patients having age less than 18 years and more than 50 years Patients having systemic disorders like, Hypertension, diabetes mellitus, Thyroidism etc.

结局指标

主要结局

Weight loss

时间窗: 0th, 21st, 42nd

次要结局

  • Reduction in skin fold thickness in Middle portion of biceps and triceps muscle, Anterior surfeace of mid thigh region, Abdominal muscle at umbilicus, Subscapular region.(Anthropmetric changes in Neck, Abdomen, Mid arm, Waist, Mid thigh)

研究者

发起方
Dr Santhosh N
申办方类型
Other [Self sponsored pg dissertation work]
责任方
Principal Investigator
主要研究者

Dr Santhosh N

KAHERS Shri BMK Ayurveda college

研究点 (1)

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