Innovative Hand Rehabilitation System With Synchronized Contralateral Haptic Feedback
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Oxygenated hemoglobin (HbO)
研究概览
简要总结
Previous studies have found that graded motor imagery (GMI) training can provide continuous activation of the cerebral cortex compared to traditional rehabilitation therapy. One of the steps in this strategy, mirror therapy, has also been widely used in the clinical treatment of hemiplegic patients. Also, comparing with traditional rehabilitation treatments, mirror therapy can continuously provide cortical activation. Besides, several studies indicated that game-based interventions contribute to brain activation in the elderly due to their interest can improve users' motivation in the training program execution. In addition, force control training has positive effects on hand dexterity, and specific doses of motor control training not only improve motor function but also have positive effects on brain function.
Currently, hand function training primarily focuses on range of motion, strength, and hand function, although there is comparatively less emphasis on enhancing both force control and brain function. Moreover, studies related to mirror therapy has primarily focused on the execution of functional movements, but has not explored whether hand strength control training can achieve the same training effects on the affected or non-dominant side through the concept of mirror therapy. Furthermore, the effects of combining a hand strength control system with a synchronous contralateral clip-on force feedback device on brain activation and hand function have not yet been studied. Therefore, this study aimed to investigate the effects of integration a finger force control training system with synchronous contralateral force feedback and mirror visual feedback device on brain activation and hand function, aiming to develop a clinically applicable hand rehabilitation system. Additionally, visual feedback from force control training in our study is through the hints displayed virtually on the game interface of the tablet, which were represented as the height of the targets, not as typical as actual movement-based mirror therapy or task-based mirror therapy.
Therefore, the purpose of the study is to understand the differences among training effects of integrating Graded-Pressure Haptic Device-TiPR closed-loop system and MVF; MVF and force control training, as well as isolated force control training, and to explore the training effects on hand strength, hand function and brain activation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 60 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age ranged from 20-80 years old
- •Without past medical history of musculoskeletal or neurological disorders that would affect muscle control ability or cause sensory abnormalities
- •Normal cognitive function to understand and follow the instructions
- •Able to understand Chinese, English, or Taiwanese language
排除标准
- •With a history of hand-related surgeries
- •With a history of neuromuscular diseases or degenerative arthritis
- •With a history of brain injury
- •With a history of taking psychiatric medications
- •Unable to understand instructions, or have cognitive impairments
- •With a history of physical disabilities (Loss of body parts) or taking relevant medications, including heart disease, peripheral arterial disease, respiratory system diseases, dialysis, unresolved upper extremity injury, or highly addicted to smoking or alcohol
结局指标
主要结局
Oxygenated hemoglobin (HbO)
时间窗: Before and after intervention(test time:40 minutes)
The Oxygenated hemoglobin (HbO) was measured while the participants play the game under both conditions
Hand Strength
时间窗: Before and after intervention(test time:15 minutes)
Handgrip strength and pinch strength was measured respectively. JAMAR Grip Hand Dynamometer and JAMAR Hydraulic Pinch Gauge were used for the apparatus for force measurement. Pinch strength was divided into lateral pinch, tip pinch and tripod pinch. Each test will test for three times and get the average results.
Force control ability
时间窗: Before and after intervention(test time: 40 seconds for each digits)
Subjects will be asked to track the target force and presses task digit to fit the target line as accurately as possible. Dominant hand and non-dominant hand need to be evaluated.
Digit Independence (EN value)
时间窗: Before and after intervention(test time:40 seconds for each digits)
The force independence of each digit is collected from the data during force tracking test in evaluation session. The parameter of force independence is an index of five digits overall enslaving presented as EN value. Dominant hand and non-dominant hand need to be evaluated.
Purdue Pegboard Test (PPT)
时间窗: Before and after intervention(total test time for all subtest: 10 minutes)
Assess the manual dexterity and coordination for one and both hands, including one hand, two hand and assembly subtest. ( Test for dominant hand and non-dominant hand). Each subtest test for three times.
Minnesota Manual Dexterity Test (MMDT)
时间窗: Before and after intervention(total test time for all subtests:25 minutes)
Assess the eye-hand coordination ability and manual dexterity. MMDT was divided into: Turning, Placing, One hand Turning and Placing, Two hand Turning and Placing, Displacing.
次要结局
- Maximum voluntary isometric contraction (MVIC)(Every time before the initiation of game(test time:1 seconds for each digit))
研究者
Fong Chin Su
Chair Professor
National Cheng-Kung University Hospital