Serum Antimullerian Hormone Levels in Patients Who Underwent Hayman Suture for Uterine Atony During Cesarean Section
试验速览
- 阶段
- 不适用
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Change in follicle stimulating hormone level from baseline (precesarean) to post-cesarean
研究概览
简要总结
From patient charts we will review patients who had undergone cesarean section within the last 6 months and identify those who received a The Hayman uterine compression suture for uterine atony. We will also select patients who delivered a baby without recieving a Hayman suture to create a control group. Patietns will be grouped as Hayman Group if they recevied a Hayman suture during C/S and control group if thay had not recevied a Hayman suture. We will then check patient charts for post-cesarean outpatient clinic visit and select those who received ovarian reserve evaluation via hormones and antral follicle count during the visits. Finally, we are planning to investigate any correlation between Hayman suture and ovarian dysfunction.
详细描述
Hayman suture is a common technique for uterine compression to stop bleeding due to uterine atony. Hayman described placement of two to four vertical compression sutures from the anterior to posterior uterine wall without hysterectomy. It is usually employed to overcome uterine atoy dıring cesarean section. However, since the technique is relatively new, data on its safety and efficacy arelimited to a few case reports. several complications including cavity obliteration, blood entrapment and infections have been described. However, data regarding the ovarioan function is lacking.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •age 18- 40 years
- •no systemic or endocrine diseases
- •patients who had uterine artery ligation due to atony
- •healthy postpartum patients as controls
排除标准
- •patients with Polyctsitic over syndrome
- •Pregnancy with IVF or oocyte donation
- •Obese patients
- •patients with previous/present endometriosis
结局指标
主要结局
Change in follicle stimulating hormone level from baseline (precesarean) to post-cesarean
时间窗: Before cesarean section and at any follow-up visit within 6 months of cesarean section
IU/L
Change in luteinizing hormone level from baseline (precesarean) to post-cesarean
时间窗: Before cesarean section and at any follow-up visit within 6 months of cesarean section
mU/mL
Change in anti-mullerian hormone level from baseline (precesarean) to post-cesarean
时间窗: Before cesarean section and at any follow-up visit within 6 months of cesarean section
ng/dl
次要结局
- Antral follicle count in the two study groups(At any follow-up visit within 6 months of cesarean section)
研究者
Aysu Akca
Principal Investigator
Kanuni Sultan Suleyman Training and Research Hospital