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Serum AMH Levels in Patients Who Underwent Hypogastric Artery Ligation

Completed
Conditions
AMH
Registration Number
NCT03220594
Lead Sponsor
Kanuni Sultan Suleyman Training and Research Hospital
Brief Summary

To observe the effects of hypogastric artery ligation on serum antimullerian hormone levels.

Detailed Description

To measure and compare serum antimullerian hormone levels in patients who underwent hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy and postpartum control. The procedures performed as an emergency life saving method during delivery. The reasons for hypogastric artery ligation/ hypogastric artery ligation+ hysterectomy were obstetric hemorrhage mainly uterine atony.

The serum levels of antimullerian hormone were measured 6 months after the operations and compared with matching postpartum controls. Serum levels of FSH, LH, PRL and TSH were also measured 6 months after the operation. Further, antral follicle count measured along with the aforementioned blood tests.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
90
Inclusion Criteria
  • age 18- 40 years
  • no systemic or endocrine diseases
  • patients who had hypogastric artery ligation and/or hysterectomy
  • healthy postpartum patients as controls
Exclusion Criteria
  • history of chemotherapy and/or radiotherapy
  • Obese patients
  • patients with previous/present endometriosis
  • patients with PCOS

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Ovarian reserve6 months

To evaluate postoperative ovarian reserve using anti-mullerian hormones and other ovary related hormones including FSH,LH

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Kanuni SSTRH

🇹🇷

İstanbul, Turkey

Kanuni SSTRH
🇹🇷İstanbul, Turkey

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