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临床试验/NCT05723016
NCT05723016已完成不适用

Serum Anti-Müllerian Hormone Levels and Its Association With Aneuploidy Rates in Human Blastocysts

Clinica de la Mujer Medicina Reproductiva, Chile1 个研究点 分布在 1 个国家目标入组 300 人开始时间: 2018年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
300
试验地点
1
主要终点
Aneuplody rate

研究概览

简要总结

The goal of this observational study is to determine is there an association between the rates of aneuploidy and the different ranges of serum Antimullerian hormone (AMH) levels.

Retrospective, single-centre study of patients undergoing IVF and preimplantation genetic testing with aneuploidy at the blastocyst stage between January 2018 and December 2022.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

性别
Female
接受健康志愿者

入选标准

  • All started cycles planned to be followed by preimplantation genetic testing for aneuploidies (PGT-A). PGT-A is proposed to the couples for the following reasons: advanced maternal age, recurrent miscarriage, repeated implantation failure or severe male infertility factor; it is also offered to all patients with a good prognosis who desired information regarding the ploidy status of their embryos.

排除标准

  • Data from oocyte donation cycles

结局指标

主要结局

Aneuplody rate

时间窗: 4 years

次要结局

  • Miscarriage rate(4 years)
  • Clinical pregnancy rate(4 years)

研究者

发起方
Clinica de la Mujer Medicina Reproductiva, Chile
申办方类型
Other
责任方
Principal Investigator
主要研究者

Jose Antonio Moreno

MD, PhD

Clinica de la Mujer Medicina Reproductiva, Chile

研究点 (1)

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