ISRCTN94854860已完成未知
The effect of single-dose losartan on the basic effects of cognitive behavioural therapy for panic disorder -A randomized double-blind placebo-controlled trial
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Participant is willing and able to give informed consent for participation in the study and to comply with all study requirements
- •2. Aged 18 years or above
- •3. Diagnosed with DSMIV panic disorder
- •4. At least moderate avoidance of agoraphobic situations
- •*Participants with MRI contraindications (e.g. pacemaker, metal implant, left-handedness) can be included in the study but will not undergo the MRI scan study component.
排除标准
- •1. Female participant who is pregnant or breastfeeding
- •2. CNS-active medication during the last 6 weeks
- •3. Current blood pressure or other heart medication (especially aliskiren or beta blockers)
- •4. Intravascular fluid depletion
- •5. Impaired liver or kidney function
- •6. Lifetime history of epilepsy or other neurological disease, systemic infection, or clinically significant hepatic, cardiac, obstructive respiratory, renal, cerebrovascular, metabolic, endocrine or pulmonary disease or disorder which, in the opinion of the investigator, may either put the participants at risk because of participation in the study, or may influence the result of the study, or the participant’s ability to participate in the study
- •7. Lifetime history of psychosis, bipolar disorder, alcohol, medication or drug abuse or dependence; current primary depressive disorder
- •8. Insufficient English skills
- •9. Participated in another study involving certain medication during the last 6 weeks
- •10. Patient unable to refrain from benzodiazepines 48 hours before treatment and testing sessions
研究者
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