临床试验/NCT00566462

NCT00566462终止2 期

Assessment of Perampanel (E2007) on Synaptic Dopamine in Mild-moderate PD Patients: A Pilot Study With [^123I]-IBZM SPECT

Eisai Inc.3 个研究点分布在 1 个国家目标入组 1 人开始时间: 2007年10月最近更新: 2018年9月6日

适应症

干预措施

试验速览

阶段: 2 期
状态: 终止
发起方: Eisai Inc.
入组人数: 1
试验地点: 3
主要终点: Change in Striatal [^123I]-Iodobenzamine (IBZM_ Binding Following a Single Dose Carbidopa/Levodopa Challenge for 15-hours at Baseline and Week 4

研究概览研究设计入排标准研究组 & 干预措施结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This is a two-arm, double-blind, placebo-controlled study.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Double (Participant, Investigator)

入排标准

年龄范围: 30 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

未提供

排除标准

未提供

研究组 & 干预措施

perampanel

Experimental

干预措施: perampanel (Drug)

1

Placebo Comparator

干预措施: placebo (Drug)

结局指标

主要结局

Change in Striatal [^123I]-Iodobenzamine (IBZM_ Binding Following a Single Dose Carbidopa/Levodopa Challenge for 15-hours at Baseline and Week 4

时间窗: Baseline and Week 4

次要结局

Change in Caudate and Putamen [^123I]-IBZM Binding Following a Single Dose Carbidopa/Levodopa Challenge for 15-hours at Baseline and Week 4(Baseline and Week 4)

研究者

发起方

Eisai Inc.

申办方类型

Industry

责任方

Sponsor

研究点 (3)

Loading locations...

相似试验

已完成

3 期

A Study With an Open-label Extension Phase to Evaluate the Efficacy and Safety of Perampanel (E2007) Administered as an Adjunctive Therapy in Subjects With Refractory Partial-onset SeizuresPartial-onset Seizures

NCT01618695Eisai Co., Ltd.940

已完成

2 期

Dose-Tolerability Titration Study to Evaluate The Efficacy And Safety Of Perampanel (E2007) In Patients With Post-Herpetic Neuralgia (PHN)Neuralgia

NCT00592774Eisai Inc.146

已完成

3 期

A Efficacy and Safety Study of Adjunctive Perampanel in Primary Generalized Tonic Clonic SeizuresSeizure Disorder Generalized Tonic Clonic

NCT01393743Eisai Inc.163

已完成

3 期

Evaluating Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial SeizuresRefractory Partial Seizures

NCT00700310Eisai Inc.712

已完成

3 期

To Evaluate The Efficacy and Safety of E2007 (Perampanel) Given as Adjunctive Therapy in Subjects With Refractory Partial SeizuresRefractory Partial Seizures

NCT00699582Eisai Inc.389