NL-OMON32340撤回不适用
Mucoviscidosis and Inflammation, Variability through Exercise and Training: Maximal exercise test - MOVIT I
niversitair Medisch Centrum Utrecht0 个研究点目标入组 24 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 12 至 17（—）
入选标准
- •Inclusion criteria which can be applied for the CF patients:
- •- CF patients diagnosed by clinical features and a positive sweat chloride test with a homozygote *F508 mutation
- •- CF patients in a clinically stable period: clinically stable means clinically stable for at least 4 weeks, since the exacerbation period. This means no use of (extra) oral or intravenous antibiotics for at least 4 weeks
- •- CF patients with a doctor*s diagnosed acute exacerbation: this exacerbation needs treatment in the hospital with intravenous antibiotics.
- •- Age: 12 to 18 years old
- •- Sex: male and female;Inclusion criteria which can be applied for the healthy people:
- •Healthy adults:
- •- > 18 years old
- •- Sex: male and female
- •Healthy children:
- •- Age: 12 to 18 years old
- •- Sex: male and female
排除标准
- •Exclusion criteria which can be applied for the CF patients:
- •- Subjects with a physical exercise contraindication by a medical specialist
- •- Subjects with a known contra-indicatory disease for exercise testing: acute or chronic cardiovascular disease, other pulmonary diseases than cystic fibrosis, acute renal disease, acute hepatitis, metabolic disorders, hemorrhagic diseases, orthostatic hypotension 90;91
- •- Subject with a known disease which can influences the immune system: acute or chronic inflammatory diseases, acute infection*
- •- Subjects who used (inhalation) corticosteroids, and/ or immunosuppressive therapy the last month
- •- Subjects who used extra antibiotics, on top of their prophylactic antibiotic treatment (regular treatment) within 4 weeks prior to the exercise testing.*
- •- Subjects who have had a lung transplantation
- •- Subjects who smoke
- •* This exclusion criteria is not applied to CF patients with an exacerbation.;Exclusion criteria with regard to the healthy people:
- •- Subjects with a physical exercise contraindication by a medical specialist
- •- Subjects with a known contra-indicatory disease for exercise testing: acute or chronic cardiovascular disease, acute or chronic pulmonary disease, acute renal disease, acute hepatitis, metabolic disorders, hemorrhagic diseases, orthostatic hypotension 90;91
- •- Subject with a known disease which can influences the immune system: acute or chronic inflammatory diseases, acute infection*
- •- Subjects who smoke
- •- Subjects who used antibiotics, immunosuppressive therapy, and/ or (inhalation) corticosteroids within one month prior to the exercise testing
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Mucoviscidosis and Inflammation, Variability through Exercise and Training: physical exercise programCystic FibrosisMucoviscidosisNL-OMON35260niversitair Medisch Centrum Utrecht40
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