Study on the Recovery of Visual Perceptual Function Dysfunction in Patients With Diabetes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 36
- 试验地点
- 2
- 主要终点
- contrast sensitivity
研究概览
简要总结
Investigators aim to investigate the effectiveness of visual perceptual learning on visual perceptual function in participants with diabetic retinopathy and to provide novel therapeutic insights for visual functional rehabilitation in diabetic retinopathy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •moderate to severe non-proliferative diabetic retinopathy (NPDR) and proliferative diabetic retinopathy(PDR) prior to treatment(17)
- •prior pan retinal laser photocoagulation (PRP) at least 4 weeks before enrollment or vitreoretinal surgery at least 8 weeks before enrollment
- •stable clinical condition
- •best-corrected visual acuity (BCVA) > 1.0 logMAR (equivalent to a Snellen visual acuity of < 20/200)
- •clear refractive media
- •age ≤ 65 years
- •ability to comprehend the examination and training procedures
排除标准
- •significant refractive media opacity
- •psychiatric disorders, chronic alcoholism and traumatic brain injury
- •new-onset vitreous hemorrhage, myopia, strabismus, amblyopia, glaucoma and macular diseases.
结局指标
主要结局
contrast sensitivity
时间窗: From enrollment to the end of treatment at 12 weeks
The contrast sensitivity measurements include grating acuity, first-order motion stimulus perception sensitivity, second-order stationary stimulus perception sensitivity and second-order motion stimulus perception sensitivity, which represent the reciprocal of the contrast threshold.
contrast sensitivity
时间窗: From enrollment to the end of treatment at 12 weeks
The contrast sensitivity measurements include grating acuity, first-order motion stimulus perception sensitivity, second-order stationary stimulus perception sensitivity and second-order motion stimulus perception sensitivity, which represent the reciprocal of the contrast threshold.
次要结局
- The Low Vision Quality of Life Questionnaire(From enrollment to the end of treatment at 12 weeks)
研究者
Lixia Feng
Chief physician, Doctoral supervisor
The First Affiliated Hospital of Anhui Medical University