NCT01173328已完成不适用
Effects of Pursed-lip Breathing on Exercise Tolerance and Dynamic Hyperinflation in Chronic Obstructive Pulmonary Disease
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Endurance time
研究概览
简要总结
Pursed-lip breathing (PLB) has been advocated to reduce respiratory rate and improve oxygen saturation in patients with chronic obstructive pulmonary disease (COPD) at rest. Although PLB is a strategy that potentially reduces expiratory flow limitation, there are only few studies addressing its effects on exercise.
This study aimed to assess the ability of PLB to change the breathing pattern, degree of dynamic hyperinflation (DH) and arterial oxygenation in COPD patients during exercise. Exercise tolerance was evaluated by endurance time and respiratory mechanics was evaluated by forced oscillation technique.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 40 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of chronic obstructive pulmonary disease (COPD)
- •Regular treatment at Clementino Fraga Filho University Hospital (UFRJ)
排除标准
- •Exacerbation in the preceding 4 weeks
- •SpO2<85% at peak exercise
- •Other diseases that may contribute to dyspnea and exercise intolerance
研究组 & 干预措施
Pursed-lip Breathing
Experimental
干预措施: Normal Breathing (Behavioral)
Pursed-lip Breathing
Experimental
干预措施: Pursed-lip breathing (Behavioral)
结局指标
主要结局
Endurance time
时间窗: within the first 01 hour
次要结局
- inspiratory capacity(within the first 01 hour)
- oxygen saturation(within the first 01 hour)
- dyspnea(within the first 01 hour)
- forced oscillation variables(within the first 01 hour)
研究者
研究点 (1)
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