Cardiac Autonomic Modulation in Older Hypertensive Individuals Submitted to Different Types of Physical Training
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 61
- 主要终点
- Heart rate
研究概览
简要总结
Sixty-one sedentary older hypertensive individuals were randomized to four groups: continuous aerobic training (CA), interval aerobic training (IA), resistance training (R), and control (C) group. The protocol included 3 sessions of training by week for 12 weeks. C individuals were instructed to continue their usual activities. They were submitted to the passive tilt test before and after the research protocol, evaluating the heart rate (HR), low frequency (LF) and high frequency (HF) bands, detrended fluctuation analysis (DFAα1) and entropy
详细描述
The individuals were randomized into four groups: continuous aerobic training (CA), interval aerobic training (IA), resistance training (R), and control (C), which performed physical exercises three times a week for twelve weeks, with a total of 36 sessions. The tilt test was performed before and after the research protocol. Individuals in the control group were only encouraged to maintain their usual activities.
For the analysis of HRV, the baseline conditions (resting in the supine position) were determined, followed by the passive postural maneuver, which characterizes the tilt test (table til tat 70 °) in order to determine the following variables:
- HR: heart rate (sympathetic action)
- LF: Low frequency band (Modulated predominantly by the sympathetic system)
- HF: High frequency band (Modulated predominantly by the parasympathetic system)
- Entropy: data complexity or irregularity index showing that, the higher the values, the better the HRV.
- DFAα1 (short term detrended fluctuation analysis)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •men and women 60-year-old or older, extensively using prescription antihypertensive drugs, and having no previous experience with physical training -
排除标准
- •• Positive treadmill test (TT) for ischemia
- •Related left ventricular systolic dysfunction of any degree
- •Presence of arrhythmias
- •Use of β-blockers
- •Use more than seven doses of ethyl alcohol per week
- •Renal insufficiency
- •Hyper- or hypothyroidism
- •Limiting lung disease
- •Osteomioarticular impairment that would limit exercise performance
- •SBP ≥160 and/or DBP ≥ 100 mmHg on baseline
结局指标
主要结局
Heart rate
时间窗: 12 weeks
Heart rate was obtained before and after the protocol by electrocardiogram, performed before and after tilt test at each time.
Short term detrended fluctuation analysis
时间窗: 12 weeks
Short term detrended fluctuation analysis obtained before and after the protocol by electrocardiogram, performed before and after tilt test at each time.The electrical signal from the electrocardiogram was filtered and amplified. The amplified signals were processed by ananalog-digital converter (DI-720, DATAQ Instruments, Akron, OH, USA) and sampled (1000 hz per channel) by a computer program (Windaq, DATAQ, Akron, OH, USA) installed in an IBM/PC computer.
Low frequency band
时间窗: 12 weeks
Low frequency band was obtained before and after the protocol by electrocardiogram, performed before and after tilt test at each time.The electrical signal from the electrocardiogram was filtered and amplified. The amplified signals were processed by ananalog-digital converter (DI-720, DATAQ Instruments, Akron, OH, USA) and sampled (1000 hz per channel) by a computer program (Windaq, DATAQ, Akron, OH, USA) installed in an IBM/PC computer.
Entropy
时间窗: 12 weeks
Entropy was obtained before and after the protocol by electrocardiogram, performed before and after tilt test at each time.The electrical signal from the electrocardiogram was filtered and amplified. The amplified signals were processed by ananalog-digital converter (DI-720, DATAQ Instruments, Akron, OH, USA) and sampled (1000 hz per channel) by a computer program (Windaq, DATAQ, Akron, OH, USA) installed in an IBM/PC computer.
High frequency band
时间窗: 12 weeks
High frequency band was obtained before and after the protocol by electrocardiogram, performed before and after tilt test at each time.The electrical signal from the electrocardiogram was filtered and amplified. The amplified signals were processed by ananalog-digital converter (DI-720, DATAQ Instruments, Akron, OH, USA) and sampled (1000 hz per channel) by a computer program (Windaq, DATAQ, Akron, OH, USA) installed in an IBM/PC computer.
次要结局
未报告次要终点
研究者
Nereida Kilza da Costa Lima
Associated Professor
University of Sao Paulo