NCT04292236已完成不适用
The Effect of Food Supplements on Food Intake and Gut Hormone Levels
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Effect on appetite and satiety ratings
研究概览
简要总结
When a meal is eaten, nutrients activate the release of hormones from the bowel into the blood stream. Normally there is a large amount of hormone released, which tells the brain that an individual is full and to stop eating. When people gain weight and become overweight or obese, these hormone signals are reduced, resulting in these people eating more and gaining more weight. This study is investigating mechanisms which may break this cycle by using particular nutrients to restore reduced hormone levels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Obese but otherwise healthy volunteers,
- •body mass index (BMI) of 30-40 kg/m2
- •agreement to consume scheduled meals
- •ability to understand the study information sheet and instructions in English and able to provide informed consent.
排除标准
- •Not meeting any of the exclusion criteria above.
- •Major gut surgery
- •Major health problems
- •Taking medication for diabetes
结局指标
主要结局
Effect on appetite and satiety ratings
时间窗: Study day 1 and study day 2 (following meal intake at breakfast and lunch)
Effect on appetite measured as change in calorific intake
次要结局
- Effect on satiety scores(Study day 1 and study day 2 (following meal intake at breakfast and lunch))
- Effect on gut hormone levels(Study day 1 and study day 2 with samples taken every 30 min)
研究者
研究点 (1)
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