跳至主要内容
临床试验/NCT04117360
NCT04117360招募中不适用

Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dentofacial Discrepancies With Pre- and Post-Treatment Analyses

University of North Carolina, Chapel Hill1 个研究点 分布在 1 个国家目标入组 180 人开始时间: 2019年9月11日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
招募中
入组人数
180
试验地点
1
主要终点
Change in Speech Distortion Phonemes over Time

研究概览

简要总结

The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but speech pathologists do not understand why. The investigators hypothesize that open bites and underbites prevent most patients from being able to pronounce words normally and surgical correction will lead to improvement in speech. Patients will be audio recorded speaking and patients' tongue gestures ultrasound recorded before and after their jaw surgeries to observe what changes occur in their speech and tongue movements.

详细描述

Purpose: The investigators are studying how phoneme distortion is effected by jaw disproportions in dentofacial disharmony (DFD) patients and whether speech improves after orthognathic surgery and orthodontic treatment. Spectral moment and tongue gestural analysis are being used to mechanistically determine how jaw position effects speech. The investigators hypothesize that skeletal open and underbites contribute to phoneme distortion and tongue gestural changes that improve following surgical correction of jaw position. All DFD patients are already seeking treatment from orthodontics and oral surgery. The study will observe how their speech changes before and after treatment. There is no randomization or intervention involved.

Aim 1: Qualify the prevalence of auditory and visual speech distortions in the DFD population. Aim 2: Quantitatively evaluate the first spectral moment (kHz) of four articulating consonant sounds (/t/, /k/, /s/, and /?/ pronounced "sh"). Quantify and analyze the changes in speech distortions for orthognathic patients pre and post-operation. Aim 3: Evaluate tongue posture during speech with patients from Aim 2 pre and post-operation.

Participants:

Participants: Patients of the UNC dentofacial disharmony (DFD) clinic who have undergone orthognathic surgery for correction of jaw disharmonies.

Procedures (methods):

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
15 Years 至 40 Years(Child, Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Jaw surgery patient at UNC with a skeletal open bite, underbite or overjet greater than 5mm.
  • •Age 15-40 years

排除标准

  • •Hearing loss
  • •Learned English as a second language
  • •Significant regional accent, as characterized by a speech pathologist
  • •Developmental delay, performing several grade levels below age bracket
  • •history of craniofacial disorder
  • •genetic syndrome associated with known craniofacial presentation
  • •history of craniofacial trauma
  • •history of prior craniofacial surgery (excluding extractions and dental procedures)
  • •Jaw surgery without fixed orthodontic appliances

研究组 & 干预措施

Dentofacial Disharmony Patients

Dentofacial disharmony patients who are seeking jaw surgery in UNC oral and maxillofacial surgery department and are seen in UNC orthodontic dentofacial disharmony clinic.

干预措施: Orthognathic surgery and Orthodontics (Other)

结局指标

主要结局

Change in Speech Distortion Phonemes over Time

时间窗: pre-operation through 9-15 months post-operation

Audio recordings of consonant phonemes will be quantitatively analyzed using spectral moment analysis yielding mean values.

Change in Quantitative Tongue Gestures over Time

时间窗: pre-operation through 9-15 months post-operation

Ultrasound analysis of tongue posture to quantitatively describe tongue position during speech.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验