Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Dystonia, Primary
- Sponsor
- University Hospital, Lille
- Enrollment
- 28
- Locations
- 1
- Primary Endpoint
- French scale "Batterie d'Evaluation Clinique de la Dysarthrie" (Clinical Evaluation of Dysarthria) phonetic analysis.
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement disorders department for idiopathic oromandibular dystonia and matched, healthy control subjects. Voice and speech disorders had to be assessed with the phonetic analysis, perceptive analysis and motor examination modules of the "Batterie d'Evaluation Clinique de la Dysarthrie" (Clinical Evaluation of Dysarthria), the Grade, Rough, Breathy, Asthenic, Strained scale, and a computer recording. Activities of daily living had to be assessed with the Oromandibular Dystonia Questionnaire, the Voice Handicap Index and the Deglutition Handicap Index.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Both groups: Man or woman Age \> 18 years French social security French speaking: fluent
- •Oromandibular dystonia group: Idiopathic oromandibular dystonia (focal or associated to other dystonic symptoms)
- •Healthy controls group: Same age +/- 2 years than a patient from the oromandibular dystonia group Normal clinical examination
Exclusion Criteria
- •Both groups: Any pathology making the orthophonic evaluation difficult Property protection regime Deprivation of liberty -Oromandibular dystonia group: Abnormal neurological examination, except dystonic features
- •Healthy controls group: History of brain lesion Abnormal neurological examination Swallowing difficulties
Outcomes
Primary Outcomes
French scale "Batterie d'Evaluation Clinique de la Dysarthrie" (Clinical Evaluation of Dysarthria) phonetic analysis.
Time Frame: 10 minutes at baseline
To describe the clinical characteristics of dysarthria in idiopathic oromandibular dystonia. Composite score (min=best=0; max=worst=151) including three subscales: phonetic production (min=worst=0; max=best=33); simple words (min=worst=0; max=best=88); complex words (min=wost=0; max=best=30).
Secondary Outcomes
- French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): maximum phonation time(1 minute at baseline)
- French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): frequency variations(1 minute at baseline)
- French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): number of pauses.(1 minute at baseline)
- French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): total lecture time.(1 minute at baseline)
- French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): pauses duration(1 minute at baseline)
- French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): fundamental frequency(1 minute at baseline)
- French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): repetitions.(2 minutes at baseline)
- French software "Logiciel d'Evaluation Vocale Assistée" (Computer-Assisted Voice Assessment): mean vocal intensity(1 minute at baseline)
- Voice handicap index(10 minutes at baseline)
- Tohara swallowing test(5 minutes at baseline)
- Deglutition Handicap Index(10 minutes at baseline)
- Oromandibular dystonia questionnaire(10 minutes at baseline)
- Grade Rough Breathy Asthenic Strained scale(5 minutes at baseline)
- French scale "Batterie d'Evaluation Clinique de la Dysarthrie" (Clinical Evaluation of Dysarthria) phonetics characteristics(5 minutes at baseline)
- French scale "Batterie d'Evaluation Clinique de la Dysarthrie" (Clinical Evaluation of Dysarthria) perceptive analysis.(5 minutes at baseline)