Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 4
- 试验地点
- 1
- 主要终点
- Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.
研究概览
简要总结
Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema. One case report has shown that ingestion of dandelion juice could induce a beneficial effect on this type of eczema. The purpose of this study is to test whether this effect can be retrieved in other patients.
详细描述
Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients.
The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.
排除标准
- •Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.
- •Pregnancy, lactation.
- •Compositae contact allergy.
- •Liver or gall bladder disease.
- •Abnormal renal or hepatic blood tests.
研究组 & 干预措施
10 ml of dandelion juice twice daily
干预措施: dandelion juice (Drug)
结局指标
主要结局
Improvement in dyshidrotic hand eczema in the study period assessed by HECSI score.
时间窗: 3-4 weeks
次要结局
- Improvement in dyshidrotic eczema in the study period assessed by the patient (Visual Analog Scale).(3-4 weeks)
研究者
Evy Paulsen
Consultant dermatologist, Ph.D.
Odense University Hospital