Non-invasive Evaluation of Prognostic Parameters for Patients With Transjugular Intrahepatic Portosystemic Shunt (TIPS) Using a Structured Follow up Protocol 2
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Survival
研究概览
简要总结
Evaluation of non-invasive prognostic parameters in patients receiving transjugular intrahepatic portosystemic shunt (TIPS) for complications of portal hypertension. Patients are cared according to the local standardized follow up program. Clinical and laboratory data from standard patient care are evaluated for potential prognostic value.
详细描述
NEPTUN consists of liver cirrhosis receiving transjugular intrahepatic portosystemic shunt (TIPS) at the Department of Internal Medicine I, University of Bonn, Germany and receiving a structured routine evaluation and follow up program. The diagnosis of cirrhosis was based on clinical, hemodynamic and biochemical parameters, and ultrasound and/or biopsy criteria.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Insertion of TIPS according to guidelines
排除标准
- •Contraindication for TIPS
结局指标
主要结局
Survival
时间窗: up to 10 years
death, liver transplantation
次要结局
- Liver Failure(up to 10 years)
- Organ Failures(up to 10 years)
- Sarcopenia(up to 10 years)
- Acute-on-Chronic Liver Failure (ACLF)(up to 10 years)
- Ascites(up to 10 years)
- Variceal Bleeding(up to 10 years)
- Kidney Failure(up to 10 years)
- Hepatic Encephalopathy (HE)(up to 10 years)
- post-surgical survival(up to 10 years)
研究者
Michael Praktiknjo
Principal Investigator
University Hospital, Bonn