KoreaN Cohort Study for Outcome in Patients With Kidney Transplantation : A 9-year Longitudinal Cohort Study of the Kidney Transplantation (KNOW-KT)
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- overall mortality
研究概览
简要总结
KNOW-KT (KoreaN cohort study for Outcome in patients With KT: A 9-year Longitudinal cohort study of the Korean adult KT patients), funded by Korea Center for Disease Control and Prevention (KCDC) was established in 2012 by a group of transplant physicians, transplant surgeons, nephrologists, epidemiologists, and biostatisticians in Korea.
We aimed to establish an adult KT cohort, to investigate the renal allograft outcomes, mortality, complications, and to explore traditional or nontraditional risk factors for morbidity and mortality. We established a bio-bank to integrate clinical and biological information. Here, we report design and method of the KNOW-KT.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Recipients and Donors of kidney transplant
排除标准
- •Multi-organ transplant recipients
结局指标
主要结局
overall mortality
时间窗: 9 years
Allograft survival
时间窗: 9 years
defined as re-transplant or initiation of maintenance dialysis
次要结局
- cardiovascular event(9 years)
- Albuminuria(9 years)
- New onset of diabetes after transplant(9 years)
- Acute Rejection(9 years)
- Quality of Life(2 years)
研究者
Curie Ahn
Professor
Seoul National University Hospital