The Effects of Musical Dual Task Training on Attention Control and Associated Gait Stability of Patients With Mild to Moderate Dementia
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Change from Baseline on the Trail Making Test at 2 months
研究概览
简要总结
The purpose of this project is to determine if the Musical Dual Task Training program improves attention control that influences measures of gait performances under dual tasking, balance, fear of falling, and behavioral disturbance in patients with mild to moderate dementia. This Musical Dual Task Training protocol is structured with musical content and patients are required to do musical tasks including singing and playing instruments contingent on visual or auditory cues while walking. This paradigm is designed to include music making because it involves great demands on attention and memory that might elicit experience-dependent plasticity in the brain. Musical Dual Task Training is proposed to strengthen brain networking for attention control that consequently may improve the gait performances in patients with dementia, as indicated by reducing dual task cost on gait.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •a mild to moderate dementia diagnosis with Clinical Dementia Rating (CDR) score: .5, 1, or 2
- •ability to walk 10 meters independently without the use of a walker or cane, or the assistance by another person
排除标准
- •other known neurologic disorders such as stroke or Parkinson's disease
- •significant orthopedic, visual, and hearing impairment that hinders ambulation
结局指标
主要结局
Change from Baseline on the Trail Making Test at 2 months
时间窗: Baseline and at 2 months
Trail Making Test Part A requires the participants to draw lines to connect a set of 25 circles as fast as possible following the sequential order of numbers (1,2,3...25) while still maintaining accuracy. Trail Making Test Part B is in a same format, but participants are required to alternates between numbers and letters (1, A, 2, B, etc.). The circles in Part B include both numbers (1 - 13) and letters (A - L). Results for both Part A and Part B are reported as the number of seconds required to complete the task. Higher scores indicate greater impairment.
次要结局
- Change from Baseline on Walking Speed during Dual tasking at 2 Months(Baseline and at 2 months)
- Change from Baseline on the Timed Up-and-Go test at 2 Months(Baseline and 2 months)
- Change from Baseline on the 7-item Short Falls Efficacy Scale International at 2 Months(Baseline and at 2 months)
- Change from Baseline on the Cohen-Mansfield Agitation Inventory scale at 2 months(Baseline and at 2 months)
- Change from Baseline on Stride Lengths during Dual Tasking at 2 Months(Baseline and at 2 months)