The Compare the Effect of Peroperative Intravenous Single Dose Dexamethasone and the Addition of Dexamethasone to Femoral Nerve Block on Postoperative Analgesic Consumption Anf Patient Comfort in Unilateral Total Knee Arthroplasty Patients
试验速览
- 阶段
- 4 期
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- visual analog scale
研究概览
简要总结
the aim of this study was to investigate compare the effect of peroperative intravenous single dose dexamethasone and the addition of dexamethasone to femoral nerve block on postoperative analgesic consumption and patient comfort in unilateral total knee arthroplasty patients
详细描述
Total knee arthroplasty leads to severe postoperative pain. for postoperative pain control after total knee arthroplasty oral -intramuscular opioids ,patient controlled analgesia intravenous or epidural opioids, single -continuous femoral nerve block involving techniques are used.
Dexamethasone is a glucocorticoid of high potency and frequently used perioperative.Dexamethasone to the local anaesthetic solution administered trough in femoral nerve blocks significantly prolonged the analgesic effect of the local anaesthetics used on this blocks.If the analgesic efficacy of systemic treatment with dexamethasone is similar with the use of perineural wich is the safest way should be preferred for systemic use.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •between 18-65 age
- •knee arthroplasty
- •no known allergies to drugs
- •ASA 1-2 patients
排除标准
- •history of diabetes
- •history of chronic pain treatment
- •pregnancy
- •severe bronchopulmonary disease
- •systemic opioid and steroid use
研究组 & 干预措施
iv dexamethasone
perioperative 2ml 8 mg ıv dexamethasone
干预措施: iv dexamethasone (Drug)
femoral dexamethasone
femoral block was performed postoperative 30 ml 0,5 % bupivacaine added 2 ml 8 mg dexamethasone
干预措施: femoral dexamethasone (Drug)
serum physiologic
干预措施: serum physiologic (Drug)
结局指标
主要结局
visual analog scale
时间窗: postoperative 2 day
次要结局
- analgesic consumption(postoperative 2 day)
研究者
ahmet öner
resident
TC Erciyes University
