跳至主要内容
临床试验/CTRI/2025/11/097300
CTRI/2025/11/097300尚未招募2 期

A comparative clinical study to evaluate the efficacy of Aragvadha Kshara and Apamarga Kshara application in Dushta Vrana

DR NAYAK LEENA2 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2025年11月30日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
100
试验地点
2
主要终点
HEALING OF DUSTHA VRANA

研究概览

简要总结

Healing of vrana is a natural process, yet it is inhibited by various factors and leads into Dushta Vrana. If the wounds are not treated properly it may lead to secondary infections, delayed healing, gangrene, etc. Sometime skin grafting is also indicated when wound is deep and larger in size. “Chronic wound is a wound that has failed to proceed through an orderly and timely process to produce anatomic and functional integrity”. To achieve good approximation, early healing and acceptable scar without complications Acharya Sushruta has elaborately explained 60 types of procedures (Shastiupakramas).  Also mentioned use of Kshara in Shashtiupakrama. In Ksharapakavidhi Adhyaya, Acharya Sushruta mentioned about dravyas which can be used for Kshara and indicated in the treatment of Dushta Vrana. Among these drugs Aragvadha is also one. Aragvadha kshara is such a kshara which is neither included in Kshara dwaya, Kshara traya, Kshara panchaka, Ksharastaka nor frequently used for the management of wounds. As Aragavadha (Cassia fistula Linn) is easily available, cost effective and non-controversial which is frequently used for the management of kustha, jwara, vibanddha etc. and no clinical research has been carried out by using Aragvadha kshara in Dushta Vrana. So keeping this in view A comparative clinical study to evaluate the efficacy of Aragvadha Kshara and Apamarga Kshara application in Dushta Vranawas conducted.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • A.Patients with controlled type 2 diabetis melitus B.Subjects suffering from non-healing ulcer / wound.
  • bad smell (Puti Gandha), abnormal colour (Vikruta Varna) with profuse discharge (Srava), severe pain (Vedana), deformity (Vikruti), Hypergranuation (utsanna mamsa), Itchhing(Kandu), Hard(Kathina) and longer healing time C.Size of the Dushta vrana will be of 10cm.

排除标准

  • A.Patient with Un Controled Diabetes Mellitus, Tubericulosis Malignancy.
  • B.Subjects with disorders like Tuberculosis, Leprosy, HIV, Vascular ulcers, Decubitus ulcers, Malignancy and underlying bony lesions.

结局指标

主要结局

HEALING OF DUSTHA VRANA

时间窗: HEALING OF DUSTHA VRANA | CONVERSATION OF DUSTHA VRANA INTO SHUDDHA VRANA WITH IN 4 WEEKS OR 28 DAYS

次要结局

  • BETTER HEALING OF DUSTHA VRANA AND CONVERSION OF DUSTHA VRANA IN TO SHUDDHA VRANA(MUCH IMPROVEMENT SEEN WITH IN 6 WEEKS OR 42 DAYS)

研究者

发起方
DR NAYAK LEENA
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Nayak Leena

N.K.JABSHETTY AYURVEDIC MEDICAL COLLEGE AND PG CENTRE BIDAR

研究点 (2)

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