Mindfulness Meditation in Bone Marrow Transplantation
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 241
- 试验地点
- 5
- 主要终点
- Psychological functioning
研究概览
简要总结
The main purpose of this study is to examine techniques to help patients cope better with the stem cell/bone marrow transplant procedure.
详细描述
Patients will be assigned to one of three study groups:
- receives the normal standard care;
- meets with an oncology nurse educator, in addition to the regular nurses on the transplant team. The nurse educator will provide information and answers to patient's questions about the stem cell/bone marrow transplant experience; or
- is taught mindfulness meditation by a nurse who is trained to be a mindfulness instructor and by an audio CD.
Mindfulness meditation is a technique that may help in coping with the stress and difficulties associated with cancer and undergoing a stem cell/bone marrow transplant. It involves learning to be in the present moment by paying attention to your breathing, sights, and sounds, and to sensations you may be experiencing, or thoughts and feelings you may be having.
Mindfulness meditation has been shown to be helpful to patients in the clinic who have cancer and other medical conditions.
Patients, regardless of random group assignment, will complete a questionnaire 8 different times, from before they are admitted to the hospital until 6 months after discharge.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- None
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Autologous stem cell transplantation for hematologic malignancy
- •First transplant
- •21 years of age or older
- •Speaks and understands English
排除标准
- •Planned tandem (more than one) transplant
- •Taking corticosteroids on a regular basis for a chronic condition
- •Prior formal mindfulness meditation training
- •Significant cognitive impairment and/or confirmed psychosis or thought disorder
结局指标
主要结局
Psychological functioning
时间窗: 1 year
次要结局
- Hospital length of stay and re-hospitalizations(1 year)
- Transplant related complications(1 year)
- Physical symptoms(1 year)
- Quality of life(1 year)
- Medication use(1 year)
- Number of days to bone marrow engraftment(1 year)
- Urinary stress hormones (cortisol and catecholamines)(1 year)
研究者
Susan Bauer-Wu, PhD, RN, FAAN
Professor
University of Virginia