Racial Differences in Yoga-Induced Cardiovascular and Immune Responses
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 2
- 主要终点
- Inflammatory markers
研究概览
简要总结
The purpose of this study is to 1) determine whether racial differences are evident in resting arterial stiffness and ambulatory blood pressure between African Americans and Caucasians 2) compare heart rate, blood pressure and cytokine production responses to exercise (yoga) between African Americans and Caucasians; 3) compare isokinetic muscular strength between racial groups; and 4) determine if correlations exist between these measures.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •Men between the ages of 18 and 39 (25 African American and 25 Caucasian) that are not professional or collegiate athletes
- •Must exercise at least 3 days per week and have no more than 1 month of yoga practice.
排除标准
- •Having stage 2 hypertension (>130 mmHg for systolic / >90 mmHg for diastolic) or higher or having taken BP medications within the 3 months prior to testing
- •Infection within the previous 4 weeks
- •Known renal disease
- •Prior myocardial infarction
- •Known coronary artery disease
- •Personal history of stroke
- •Heart failure
- •Cardiac arrhythmias
- •Chronic obstructive pulmonary disease
- •Recent chest pain or dyspnea
- •Orthopedic limitations that preclude the execution of yoga postures
- •Current insulin dependence
- •Chronic inflammatory conditions
- •Blindness or deafness as participants will need to follow a yoga DVD in order to complete the session
- •Having practiced yoga for more than 1 month
- •Having parents of mixed racial backgrounds (i.e. both parents must be Caucasian or African American)
- •Not being African American or Caucasian
- •Being a professional or collegiate athlete
- •Being insulin-dependent
结局指标
主要结局
Inflammatory markers
时间窗: Once immediately after the 1-hour yoga session
Blood samples will be obtained and analyzed for interleukin-6 and tumor necrosis factor alpha
Arterial stiffness
时间窗: Once at baseline
Cardio-ankle vascular index
Isokinetic strength
时间窗: Once at baseline
Isokinetic leg extension and flexion strength assessments at 60,120,210,300, and 400 degrees per second
Ambulatory blood pressure
时间窗: Once at baseline
24 hours of ambulatory blood pressure monitoring
次要结局
未报告次要终点