Assessment of the Outcome of Endodontic Treatment Using Cone Beam Computed Tomography-A Prospective Study
试验速览
- 阶段
- 不适用
- 入组人数
- 65
- 主要终点
- Periapical periodontium health
研究概览
简要总结
The aim of the study is to assess the correlation between pre-obturation bacterial detection using fluorescence amplification and outcome of endodontic treatments. Thus, enabling a suitable detection threshold to predict the likelihood of treatment failure. This has the potential to be used a bench side tool in general dental practice to act as a surrogate endpoint for clinicians performing root canal treatment.
详细描述
Pre-obturation root canal samples were taken using paper points from patients undergoing primary root treatments. The samples were analyzed using a fluorescent spectrometer and a molecular fluorescent vital dye (Calcein AM).
Pre-operative and 1-year post-operative periapical radiographs and Cone Beam Computed Tomography (CBCT) scans were assessed by two calibrated expert examiners to evaluate the outcome of the root canal treatments.
The use of a chairside bacterial stain can allow the clinician to predict the outcome of treatment with confidence. Sampling the root canal space with endodontic paper points followed by ex-situ fluorescent staining and analysis provides a patient-friendly, simple to use and rapid way of predicting root canal treatment outcome.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with at least one tooth diagnosed with the endodontic disease.
- •teeth that were tender to percussion and palpation.
- •teeth that had a sinus tract and/ swelling.
- •Both primary treatment teeth and teeth which had already been root treated were considered.
排除标准
- •Patients were excluded if they were pregnant.
- •Immunosuppressed patients.
- •Non-restorable teeth.
- •Teeth with a periodontal probing depth greater than 3mm.
- •Teeth with apical radiolucencies with the longest dimension above 1.2cm.
结局指标
主要结局
Periapical periodontium health
时间窗: One year
Assess the health of periapical periodontium of a tooth by examining the CBCT image
次要结局
未报告次要终点