Effect of Perioperative Intravenous Lidocaine Infusion on Postoperative Recovery in Patients Undergoing Arthroscopic Rotator Cuff Repair Under General Anesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 98
- 试验地点
- 1
- 主要终点
- Fentanyl requirement using IV PCA
研究概览
简要总结
Arthroscopic rotator cuff repair is a commonly performed procedure but is known to cause significant postoperative pain. Effective analgesia after rotator cuff repair is crucial in improving the well-being of the patient but also to ensure long-term rehabilitation. The most commonly used analgesic for acute postoperative pain is opioids. However, the use of opioids is accompanied by several side effects which include but are not limited to nausea/vomiting, urinary retention, itching sensation and sometimes dizziness, respiratory depression and hypotension in higher doses. As of late, many efforts are aimed toward decreasing the use of opioids by using multimodal analgesia. Among such methods, intravenous lidocaine has been reported to be effective, safe and economic in various procedures. However, the existing evidence is mostly focused on laparoscopic procedures. The present study aims to find whether perioperative infusion of lidocaine is able to decrease opioid requirements after surgery and also improve postoperative pain compared to placebo in patients undergoing arthroscopic rotator cuff repair.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 19 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •ASA class 1-3 adults over 19 years scheduled for elective arthroscopic rotator cuff repair
排除标准
- •Known allergies to lidocaine or propofol
- •Cardia arrhythmia
- •History of epilepsy or seizures
- •Liver/kidney failure
- •History of recent strong opioid use
研究组 & 干预措施
IV lidocaine
Perioperative IV lidocaine infusion
干预措施: Lidocaine (Drug)
Normal saline
Perioperative IV normal saline infusion
干预措施: Normal saline (Drug)
结局指标
主要结局
Fentanyl requirement using IV PCA
时间窗: 24hours after surgery
Dose of fentanyl infused via IV PCA machine during first 24 hours after surgery.
次要结局
未报告次要终点
