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临床试验/NCT05093491
NCT05093491已完成不适用

Ultrasonographic Evaluation of Respiratory Muscles in Stroke Patients and Correlation With Pulmonary Function Tests

Istanbul Physical Medicine Rehabilitation Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2020年12月25日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
70
试验地点
1
主要终点
Forced expiratory volume 1 second [FEV1]

研究概览

简要总结

Ultrasonographic evaluation of respiratory muscle thickness in stroke patients, determination of its correlation with pulmonary function test (PFT) , and the first evaluation method to determine respiratory rehabilitation goals and to use it in the follow-up of the effectiveness of the treatment.

详细描述

The study is planned as a cross-sectional prospective study. Healthy volunteers and stroke patients who are planned to be hospitalized in the Stroke clinic for rehabilitation in Istanbul Physical Medicine Rehabilitation Training and Research Hospital are evaluated and included in the study according to the inclusion and exclusion criteria.

Demographic data of patients (gender, age, height, weight, body mass index, comorbidity status, smoking/alcohol use, dominant extremity, stroke etiology, duration, side), functional status (Brunnstrom stages, Functional Ambulation Scale (FAS), Daily Living Activity (ADL) Index), Pulmonary Function Test (PFT) measurement results and bilateral diaphragm and abdominal muscle thicknesses and thickening ratio in ultrasonography, demographic data of healthy volunteers (gender, age, height, weight, body mass index, comorbidity status, smoking/alcohol use, dominant side), PFT measurement results and the dominant side diaphragm and abdominal muscle thicknesses and thickening ratio in ultrasonography is done and included in the study.

In the ultrasonographic evaluation of the participants, using a 7-12 Mhz linear Probe, measurements are made of the diaphragm at the end of tidal expiration and forced inspiration, abdominal muscles at the end of tidal expiration and at the end of forced expiration, while all respiratory muscles are lying in the supine position. Diaphragm thickness is measured between the 8th and 9th ribs at the level of the anteroaxillary line, rectus abdominis; 4 cm lateral of the umbilicus, transversus abdominis, external oblique, internal oblique muscles' measurement is made from the middle of the lowest part of the 12. rib and the highest point of the iliac crest and 2.5 cm in front of the midaxillary line. All measurements are repeated 3 times and the average value will be recorded.

Vital capacity[VC], forced vital capacity [FVC], forced expiratory volume 1 second [FEV1] , FEV1/FVC, maximal expiratory flow rate [PEF], maximum inspiratory pressure [MIP] maximum expiratory pressure [MEP] in patients' PFT ] measurement results are checked.

Intragroup and intergroup data are compared.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
30 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Ischemic or Hemorrhagic stroke patients
  • Stroke duration >6 months
  • Mini-mental test score >24

排除标准

  • Individuals with acute or chronic lung disease
  • Patients with a history of thoracic or abdominal surgery
  • Patients with other neuromuscular diseases
  • Aphasia type with impaired understanding
  • Facial paralysis

结局指标

主要结局

Forced expiratory volume 1 second [FEV1]

时间窗: 1 day (a single point in time)

\>%80 is normal results

Diaphragma and Abdominal Muscle Thickness and thickening ratio

时间窗: 1 day (a single point in time)

Diaphragma and Abdominal Muscle ultrasonographic millimetric measurement

Forced vital capacity [FVC]

时间窗: 1 day (a single point in time)

\>%80 is normal results

Maximal expiratory flow rate [PEF]

时间窗: 1 day (a single point in time)

\>%80 is normal results

Maximum inspiratory pressure [MIP],

时间窗: 1 day (a single point in time)

\>80cmH2O is normal results

FEV1/FVC

时间窗: 1 day (a single point in time)

\>%80 is normal results

Maximum expiratory pressure [MEP]

时间窗: 1 day (a single point in time)

\>95cmH2O is normal results

次要结局

  • Functional Ambulation Scale (FAS)(1 day (a single point in time))
  • Daily Living Activity (ADL) Index(1 day (a single point in time))
  • Brunnstrom stages(1 day (a single point in time))

研究者

发起方
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
申办方类型
Other Gov
责任方
Sponsor

研究点 (1)

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