Sonography-guided Pericapsular Nerve Group Block for Hip Arthroplasty
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 71
- 试验地点
- 1
- 主要终点
- Highest VAS score in recovery room
研究概览
简要总结
In this study, the investigator will examine the efficacy of Pericapsular nerve group (PENG) block in hip arthroplasty as a post-operative pain management technique, study the analgesia, opioid-sparing effects and motor-blocking effects of the PENG block
详细描述
PENG Block group (PG) will receive 0.5%Ropivacaine in 20 ml of saline. Sham Block group (SG) will receive 20 ml of saline Patient will be sedated with IV midazolam before nerve block. After peripheral nerve block ,general anesthesia will be conducted using sufentanyl, propofol and rocuronium for induction and propofol and sevoflurane for maintenance. Tests will be operated after procedure，and recorded up to 48 hours after surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients scheduled for hip arthroplasty
排除标准
- •allergy to local anesthetics
- •infection at the injection site
- •patients receiving opioids for chronic analgesic therapy
- •other lower limb neuropathies
- •inability to comprehend visual analog scale (VAS)
- •preexist cognitive dysfunction
结局指标
主要结局
Highest VAS score in recovery room
时间窗: before recovery room discharge(up to 2 hours after surgery end)
Highest VAS score reported in recovery room,patient will be asked questions to measure the highest VAS score experienced in the recovery room before discharge. If the patient had a unexpected long stay at recovery room, the question will be asked at the time point "2 hours after surgery end"
次要结局
- VAS at rest(day0 ,day1 ,day2)
- highest VAS at period(day0 ,day1 ,day2)
- quadriceps strength(day0 , day1 ,day2)
- total opioid consumption(up to 2 days after surgery)
- PONV rate(day0 ,day1 ,day2)
- Fall incident happened(up to 2 days after surgery)
- Nerve block range(day0 , before discharge from PACU(up to 2 hours after surgery end))
研究者
Xiangcai Ruan, MD, PhD, Vice-Director in Dept Anesth & Pain
Professor
Guangzhou First People's Hospital