The Combined Effect of Vitamin D3 and Omega-3 Supplements on Serum Leptin and Glycated Hemoglobin (Hb A1C) Levels in Jordanian People With Vitamin D Deficiency.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 146
- 试验地点
- 2
- 主要终点
- HbA1C
研究概览
简要总结
The Combined effect of Vitamin D3 and Omega-3 supplements on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency.
详细描述
Nothing is published in the literature about effect of vitamin D3 (VD3) and omega-3 fatty acids (omega-3FA) on serum leptin and glycated hemoglobin ( HbA1C)
This study will be conducted to investigate effect of VD3 and omega-3FA alone and with each other on serum leptin and Glycated hemoglobin (Hb A1C) levels in Jordanian people with vitamin D deficiency.
This randomized, controlled clinical trial will be designed to test effects of 50,000 IU VD3 weekly and 1000 mg omega-3FA daily for eight weeks, separately and with each other, on on serum leptin and Glycated hemoglobin (Hb A1C) levels .
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 25 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •jordanian people aged 25-55
- •medical diagnosis of vitamin D deficiency ( VD <25 ng/ ml)
排除标准
- •Blood disorders including
- •thalassemia
- •sickle cell disease
研究组 & 干预措施
VD3 group
dietary supplement : VD3 group treated with 50000 IU VD3/ week for 8 weeks
干预措施: VD3 group (Dietary Supplement)
omega 3- FA group
dietary supplement : omega 3- FA group 1000 mg wild salmon and fish oil complex (contain 300 mg of omega 3-FA) once daily for 8 weeks
干预措施: omega 3 FA group (Dietary Supplement)
VD3 and omega 3 FA group
dietary supplement : VD3 and omega-3FA 50000 IU VD3/week for 8 weeks and 1000 mg wild salmon and fish oil complex (contain 300 mg of omega 3-FA) once daily for 8 weeks
干预措施: VD3 and omega- 3FA group (Dietary Supplement)
control group
no intervention was given
干预措施: control group (Other)
结局指标
主要结局
HbA1C
时间窗: 8 weeks
plasma concentration of HbA1C
leptin
时间窗: 8 weeks
serum level of leptin
VD 3
时间窗: 8 weeks
Serum level of 25-hydroxyvitamin D
次要结局
未报告次要终点